Π‘ΠΏΠΈΡΠΎΠΊ Π»ΡΡΠ΅ΡΠ°ΡΡΡΠΈ.
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ΠΊΠ»ΡΡΠΈΠ½ Π΄ΠΎ ΡΠΈΡΠΏΠ»Π°ΡΠΈΠ½Π°
Sakahura C, Sweeney EA, Shirahama T, Igarashi Y, Hakomori S, Tsujimoto H, Imanishi T, Ogaki M, Yamazaki J, Hagiwara A, Yamaguchi T, Sawai K, Takahashi T. Overexpression of bax sensitizes breast cancer MCF-7 cells to cisplatin and etoposide. Surg Today 1997, 27 (7): 676β9. Ju JF, Banerjee D, Lenz HJ, Danenberg KD, Schmittgen TC, Spreas CP, Schonthal AH, Manno DJ, Hochhauser D, Bertino JR… Π§ΠΈΡΠ°ΡΡ Π΅ΡΡ >
Π‘ΠΏΠΈΡΠΎΠΊ Π»ΡΡΠ΅ΡΠ°ΡΡΡΠΈ. ΠΠ΅Ρ Π°Π½ΡΠ·ΠΌΠΈ ΡΠ΅Π·ΠΈΡΡΠ΅Π½ΡΠ½ΠΎΡΡΡ ΠΏΡΡ Π»ΠΈΠ½Π½ΠΈΡ ΠΊΠ»ΡΡΠΈΠ½ Π΄ΠΎ ΡΠΈΡΠΏΠ»Π°ΡΠΈΠ½Π° (ΡΠ΅ΡΠ΅ΡΠ°Ρ, ΠΊΡΡΡΠΎΠ²Π°Ρ, Π΄ΠΈΠΏΠ»ΠΎΠΌ, ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½Π°Ρ)
Π§Π΅Ρ ΡΠ½ ΠΠ€. Π ΠΎΠ»Ρ ΠΏΠ»Π°Π·ΠΌΠ°ΡΠΈΡΠ½ΠΈΡ ΠΌΠ΅ΠΌΠ±ΡΠ°Π½ Π½ΠΎΡΠΌΠ°Π»ΡΠ½ΠΈΡ Ρ ΠΏΡΡ Π»ΠΈΠ½Π½ΠΈΡ ΠΊΠ»ΡΡΠΈΠ½ Π² ΠΌΠ΅Ρ Π°Π½ΡΠ·ΠΌΡ ΡΠ΅Π°Π»ΡΠ·Π°ΡΡΡ ΡΠΈΡΠΎΡΠΎΠΊΡΠΈΡΠ½ΠΈΡ Π΅ΡΠ΅ΠΊΡΡΠ² ΠΊΠΎΠΎΡΠ΄ΠΈΠ½Π°ΡΡΠΉΠ½ΠΈΡ ΡΠΏΠΎΠ»ΡΠΊ ΠΏΠ»Π°ΡΠΈΠ½ΠΈ [ΠΠ²ΡΠΎΡΠ΅Ρ Π΄ΠΈΡ … Π΄ΠΎΠΊΡ ΠΌΠ΅Π΄ Π½Π°ΡΠΊ]. ΠΠΈΠ΅Π²: ΠΠΠΠΠ , 1994. 40 ΡΡ.
- 2. Scanlon KJ, Kashani-Sabet M, Tone T, Funato T. Cisplatin resistance in human cancers. Pharmacol Ther 1991; 52:385−406.
- 3. Gately DP, S.B.Howell SB. Cellular accumulation of the anticancer agent cisplatin. Br J Cancer 1993; 67:1171−6.
- 4. Ohmori T, Morikage T. The mechanism of the difference in cellular uptake of platinum derivatives in non-small cell lung cancer cell line (PC-14) and its cisplatin-resistant subline (PC-14/CDDP). Jpn J Cancer Res 1993; 84: 83−92.
- 5. Scanlon KJ, Safistein RL, Thies H, Gross RB, Waxman S, Guttenplan JB. Inhibition of amino acid transport by cis-diamminedichloroplatinum (II) derivatives in L1210 murine leukemia cells. Cancer Res 1983; 43: 4211−5.
- 6. Andrews PA, Velury S, Mann SC, Howell SB. Cis-diamminedichloroplatinum II accumulation in sensitive and resistant human ovarian carcinoma cells. Cancer Res 1988; 48: 68−73.
- 7. Richon VM, Schulte N, Eastman A. Multiple mechanisms of resistance to cis-diamminedichloroplatinum (II) in murine leukemia L1210 cells. Cancer Res 1987 47: 2056;61.
- 8. Zaman GJR, Lakelma J, Tellingen O, Beijnen J, Dekker H, Paulusma C, Oude Elferink RPJ, Baas F, Borst P. Role of glutathione in the export of compaunds from cells by the multidrug-resistance-associated protein. Proc Natl Acad Sci USA 1995; 92:7690−4.
- 9. Muller V, Meijer C, Zaman GJR. Overexpression of the gene encoding the multidrug resistance-assiciated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc Natl Acad Sci USA 1994; 91: 13 033−7.
- 10. Ishikawa T, Ali-Osman F. Glutathione-associated cis-diamminedichloroplatinum (II) metabolism and ATP-dependent efflux from leukemia cells. J Biol Chem 1993; 268: 20 116−25.
- 11. Laurent G, Erickson LC, Sharkey NA, Kohn KW. DNA cross-linking and cytotoxicity induced by cis-diamminedichloroplatinum (II) in human normal and tumor cell lines. Cancer Res 1981; 41: 3347−51.
- 12. Sorenson CM, Barry MA, Eastman A. Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin. J Natl Cancer Inst 1990; 82: 749−55.
- 13. Olivero OA, Chang PK, Lopez-larraza DM, Semino-Mora MC, Poirier MC. Preferential formation and decreased removal of cisplatin-DNA adducts in chinese hamster ovary cell mitochondrial DNA as compared to nuclear DNA. Mutat Res 1997, 391(1−2): 79−86.
- 14. Giurgiovich AJ, Diwan BA, Olivero OA, Anderson LM, Rice JM, Poirier MC. Elevated mitochondrial cisplatin-DNA adduct levels in rat tissues after transplacental cisplatin exposure. Carcinogenesis 1997, 18(1): 93−6.
- 15. Gorczyca W, Gong I, Ardelt B, Traganos F, Darzynkiewicz Z. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res 1993, 53(13): 3186−92.
- 16. el Alaoui S, Lawry J, Griffin M. The cell cycle and induction of apoptosis in a hamster fibrosarcoma cell line treated with anticancer drugs: its importance to solid tumor chemotherapy. J Neurooncol 1997, 31(1−2): 195−207.
- 17. Vaisman A, Varchenko M, Said I, Chaney SG. Cell cycle changes associated with formation of Pt-DNA adducts in human ovarian carcinoma cells with different cisplatin sensitivity. Cytometry 1997, 27(1): 54−64.
- 18. Nishio K, Saigo N. Effect of cisplatin on cell cycle regulators. Gan To Kagaku Ryoho 1994, 21(3): 289−94.
- 19. Dimanche-Boitrel MT, Micheau O, Hamman A, Haugg M, Eymin B, Chauffert B, Solary E. Contribution of the cyclin-dependent kinase inhibitor p27KIP1 to the confluence-dependent resistance of HT 29 human colon carcinoma cells. Int J Cancer 1998, 77(5): 796−802.
- 20. Gill JS, Mindebank AJ. Cisplatin-induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle. J Clin Invest 1998, 101(12): 2842−50.
- 21. Megyesi J, Safirstein RL, Price PM. Induction of p 21 WAF1? CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure. J Clin Invest 1998, 101(4): 777−82.
- 22. Otto AM, Paddenberg R, Schubert S, Mannherz HG. Cell cycle arrest, micronucleus formation, and cell death in growth inhibition of MCF-7 breast cancer cells by tamoxifen and cisplatin. J Cancer Res Clin Oncol 1996, 122(10): 603−612.
- 23. Boersma AW, Nooter K, Oostrum RG, Stoter G. Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in chinese hamster ovary cells cultures treated with cisplatin. Cytometry 1996, 24(2): 123−130.
- 24. Ormerod MG, O`Neill C, Robertson D, Helland LR, Harrap KR. Cis-diamminedichloroplatinum (II)-induced cell death through apoptosis in sensitive and resistant human ovarian carcinoma cell lines. Cancer Chemother Pharmacol 1996, 37(5): 463−471.
- 25. Uslu R, Jewett A, Bonavida B. Sensitization of human ovarian tumor cells by subtoxic CDDP to anti-fas antibody mediated cytotoxicity and apoptosis. Gynecol Oncol 1996, 62(2): 282−91.
- 26. Fulda S, Sieverts H, Friesen C, Herr I, Debatin KM. The CD95(APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells. Cancer Res 1997, 57(17): 3823−9.
- 27. McGahon AJ, Costa Pereira AP, Daly L, Cotter TG. Chemotherapeutic drug-induced apoptosis in human leukaemic cells is independent of the Fas (APO-1/CD95) receptor/ligand system. Br J Haematol 1998, 101(3): 539−47.
- 28. Antoku K, Liu Z, Johnson DE. Inhibition of caspase proteases by CrmA enhances the resistance of human leukemia cells to multiple chemotherapeutic agents. Leukemia 1997, 11(10): 1665−72.
- 29. Chen Z, Naito M, Mashima T, Tsuruo T. Activation of actin-cleavable interleukin 1 beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells. Cancer Res 1996, 56(22): 5224−9.
- 30. Marissen WE, Lloyd RE. Eukariotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells. Mol Cell Biol 1998, 18(12): 7565−74.
- 31. Kraker AJ, Moore CW. Accumulation of cis-diamminedichloroplatinum (II) and platinum analogues by platinum-resistant murine leukemia cells in vitro. Cancer Res 1988; 48: 9−13.
- 32. Eichholtz-Wirth H, Hietel B. The relationship between cisplatin sensitivity and drug uptake into mammalian cells in vitro. Br J Cancer 1986; 54: 239−43.
- 33. Kawai K, Kamatani N, Georges E, Ling V. Identification of a membrane glycoprotein overexpression in murine lymphoma sublines resistant to cisdiamminedichloroplatinum (II). J Biol Chem 1990; 265: 13 137−42.
- 34. Ishikawa T, Wright CD, Ishizuka H. GS-X pump Is functionally overexpressed in cis-diamminedichloroplatinum (II)-resistant human leukemia HL-60 Cells and downregulated by cell differentiation. J Biol Chem 1994; 269: 29 085−93.
- 35. Goto S, Yoshido K, MoriKawa T, Urata Y, Suzuki K,. Kondo T. Augmentation of transport for cisplatin-glutathione adduct in cisplatin-resistant cancer cells. Cancer Res 1995; 55: 4297−301.
- 36. Veneroni S, Zaffaroni N, Daidone MG, Benini E, Villa R, Silvestrini R. Expression of P-glycoprotein and in vitro or in vivo resistance to doxorubicin and cisplatin in breast and ovarian cancers. Eur J Cancer 1994; 30A: 1002−7.
- 37. Jedlitschky G, Leier J, Buchholz U, Barnouin K, Kurz G, Keppler D. Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res 1996; 56: 988−94.
- 38. Okuyama T, Maehara Y, Endo K, Baba H, Adachi Y, Kuwano M, Sugimachi K. Expression of glutathione S-transferase-pi and sensitivity of human gastric cancer cells to cisplatin. Cancer 1994; 74: 1230−6.
- 39. Awasthi S, Sharma R, Singhal SS, Herzog NK, Chaubey M, Awasthi YC. Modulation of cisplatin cytotoxicity by sulphasalazine. Br J Cancer 1994; 70: 190−4.
- 40. Bongers V, Snow GB, Braakhuis BJM. The role of glutathione S-transferases in head and neck squamous cell carcinogenesis. Eur J Cancer 1995; 31B: 349−54.
- 41 Minagawa Y, Kigawa J, Ishihara H, Itamochi H, Terakawa N. Synergistic enhancement of cisplatin cytotoxicity by SN-38, an active metabolite of CPT-11, for cisplatin-resistant HeLa cells. Jpn J Cancer Res 1994; 85: 966−71.
- 42. Boscia RE, Korbut T, Holden SA, Ara G, Teicher BA. Interaction of topoisomerase I inhibitors with radiation in cis-Diamminedichloroplatinum (II)-sensitive andresistant cells in vitro and in the FSAIIC fibrosarcoma in vivo. Int J Cancer 1993; 53: 118−23.
- 43. Kikuchi Y, Hirata J, Yamamoto K, Ishi K, Kita T, Kudoh K, Tode T, Nagata I, Taniguchi K, Kuwano M. Altered expression of ?-glutamylcysteine synthetase, metallothionein and topoisomerase I or II during acquisition of drug resistance to cisplatin in human ovarian cancer cells. Jpn J Cancer Res 1997; 88: 213−7.
- 44. Hirata J, Kikuchi Y, Kita T, Imaizumi EE, Tode T, Ishii K, Kudoh K, Nagata I. Modulation of sensitivity of human ovarian cancer cells to cis-diamminedichloroplatinum (II) by 12-O-tetradecanoylphorbol-13-acetate and D, L-Buthionine-S, R-Sulphoximine. Int J Cancer 1993; 55: 521−7.
- 45. Sugimoto C, Matsukawa S, Fujieda S, Noda I, Tanaka N, Tsuzuki H, Saito H. Involvement of intracellular glutathione in induction of apoptosis by cisplatin in a human pharyngeal carcinoma cell line. Anticancer Res 1996; 16: 675−80.
- 46. Pendyala L, Perez R, Weinstein A, Zdanowicz J, Creaven PJ. Effect of glutathione depletion on the cytotoxicity of cisplatin and iproplatin in a human melanoma cell line. Cancer Chemother Pharmacol 1997, 40 (1): 38−44.
- 47. Kurokawa H, Nishio K, Ishida T, Arioka H, Fukuoka K, Nomoto T, Fukumoto H, Yokote H, Saijo N. Effect of glutathione depletion on cisplatin resistance in cancer cells transfected with the? -glutamylcysteine synthetase gene. Jpn J Cancer Res 1997; 88: 108−10.
- 48. Campling BG, Baer K, Baker HM, Lam YM. Cole SPC. Do glutathione and related enzymes play a role in drug resistance in small cell lung cancer ctll lines? Br J Cancer 1993; 68: 327−35.
- 49. Kodera Y, Akiyama S, Isobe K, Kondo K, Ito K, Yamauchi M, Takagi H. Expression of ?-glutathione S-transferase gene (GSTP1) in gastric cancer: lack of correlation with resistance against cis-diamminedichloroplatinum (II). Eur J Cancer 1994; 30A: 2158−62.
- 50. Mellish KJ, Kelland LR, Harrap KR. In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin. Br J Cancer 1993; 68: 240−50.
- 51. Eichholtz-Wirth H, Reidel G, Hietel B. Radiation-induced transient cisplatin resistance in murine fibrosarcoma cells associated with elevated metallothionein content. Br J Cancer 1993; 67: 1001−6.
- 52. Lazo JS, Basu A. Metallothionein expression and transient resistance to electrophilic antineoplastic drugs. Semin Cancer Biol 1991; 2: 267−71.
- 53. Hishikawa Y, Abe SI, Kinugasa S, Yoshimura H, Monden N. Overexpression of metallothionein correlates with chemoresistance to cisplatin and prognosis in esophageal cancer. Oncology 1997; 54: 342−7.
- 54. Vaisman A, Vachenko M, Said I, Chaney SG. Cell cycle changes associated with formation of Pt-DNA adducts in human ovarian carcinoma cells with different cisplatin sensitivity. Cytometry 1997; 27: 54−64.
- 55. Hill BT, Scanlon KJ, Hansson J, Harstrick A, Pera M, Fichtinger-Schepman AMJ, Shellard SA. Deficient repair of cisplatin-DNA adducts identified in human testicular teratoma cell lines established from tumours from untreated patients. Eur J Cancer 1994; 30A: 832−7.
- 56. Johnson SW, Swiggard PA, Handel LM, Godwin AK, Ozols RF, Hamilton TC. Relationship between platinum-DNA adduct formation and removal and cisplatin cytotoxicity in cisplatin-sensitive and resistant human ovarian cancer cells. Cancer Res 1994, 54: 5911−6.
- 57. Turchi JJ, Li M, Henkels KM. Cisplatin-DNA binding specificity of calf high mobility group I protein. Biochem 1996; 35: 2992−3000.
- 58. Ikeda S, Ozaki K. Action of mitochondrial endonuclease G on DNA damaged by L-ascorbic acid, peplomycin, and cis-diamminedichloroplatinum (II). Biochem Biophys Res Commun 1997, 235(2): 291−4.
- 59. Bissett D, McLaughlin K, Kelland LR, Brown R. Cisplatin-DNA damage recognition proteins in human tumor extracts. Br J Cancer 1993; 67:742−8.
- 60. McLaughlin K, Coren G, Masters J, Brown R. Binding activities of cis-platin-damage-recognition proteins in human tumor cell lines. Int J Cancer 1993; 53: 662−6.
- 61. Brown R, Hirst GL, Gallagher WM, McIlwrath AJ, Margison GP, Zee AG, Anthoney DA. HMLN1 expression and cellular responses of ovarian tumor cells to treatment with cytotoxic anticancer agents. Oncogene 1997, 15(1): 45−52.
- 62. Lanzi C, Perego P, Supino R, Romanelli S, Pensa T, Carenini N, Viano I, Colangelo D, Leone R, Apostoli P, Cassinelli G, Gambetta RA, Zunino F. Decreased drug accumulation and increased tolerance to DNA damage in tumor cells with a low level of cisplatin resistance. Biochem Pharmacol 1998, 55(8): 1247−54.
- 63. Fishel R, Ewel A, Lescoe MC. Purified human MSH2 protein binds to DNA containing mismatched nucleotides. Cancer Res 1994; 54: 5539−42.
- 64. Loeb LA. Microsatellite instability: marker of a mutator phenotype in cancer. Cancer Res 1994; 54: 5059−63.
- 65. Chu G. Cellular responces to Cisplatin. J Biol Chem 1994; 269: 787−90.
- 66. Sorenson CM, Eastman A. Influence of cis-Diamminedichloroplatinum (II) on DNA synthesis and cell cycle progression in excision repair proficient and deficient hamster ovary cells. Cancer Res 1988; 48: 6703−7.
- 67. Li Q, Gardner K, Zhang L, Tsang B, Bostick-Bruton F, Reed E. Cisplatin induction of ERCC-1 mRNA expression in A2780/CP70 human ovarian cancer cells. J Biol Chem 1998, 273 (36): 23 419−25.
- 68. Husain A, He G, Venkatraman ES, Spriggs DR. BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum (II). Cancer Res 1998, 58 (6): 1120−3.
- 69. Mestdach N, Pommery N, Saucier JM, Hecquet B, Founier C, Slomianny C, Teissier E, Henichart JP. Chemoresistance to doxorubicin and cisplatin in a murine cell line. Analysis of P-Glycoprotein, topoisomerase II activity, glutathione and related enzymes. Anticancer Res 1994; 14: 869−74.
- 70. Kondo H, Kanzawa F, Nishio K, Saito S, Saijo N. In vitro and in vivo effects of cisplatin and etoposide in combination on small cell lung cancer cell lines. Jpn J Cancer Res 1994; 85: 1050−6.
- 71. Jong S, Timmer-Bosscha H, Vries EGE, Mulder NH. Effect of novobiocin on cisplatin cytotoxicity and DNA interstrand cross-link formation in a cisplatin-resistant, small-cell lung carcinoma cell line. Int J Cancer 1993; 53: 110−7.
- 72. Guchelaar H-J, Timmer-Bosscha H, Dam-Meiring A, Uges DRA, Oosterhuis JW, Vries EGE Mulder NH. Enhancement of cisplatin and etoposide cytotoxicity after all-trans retinoic-acid-induced cellular differentiation of a murine embryonal carcinoma cell line. Int J Cancer 1993; 55: 442−7.
- 73. Seki S, Hongo A, Zhang B, Akiyama K, Sarker AH, Kudo T. Inhibition of cisplatin-mediated DNA damage in vitro by ribonucleotides. Jpn J Cancer Res 1993; 84: 462−7.
- 74. Parekh HK, Simpkins H. The differential expression of citokeratin 18 in cisplatin-sensitive andresistant human ovarian adenocarcinoma cells and its association with drug sensitivity. Cancer Res 1995; 55: 5203−6.
- 75. Mirakhur B, Parekh HK, Simpkins H. Expression of the cisplatin resistance phenotype in a human ovarian carcinoma cell line segregates with chromosomes 11 and 16. Cancer Res 1996; 56: 2256−62.
- 76. Mueller H, Eppeberger U. The dual role of mutant p 53 protein in chemosensitivity of human cancers. Anticancer Res 1996, 16 (6B): 3845−8.
- 77. Kawasaki t, Tomita Y, Bilim V, Takeda M, Takahashi K, Kumanishi T. Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines with p 21/WAF1/CIP1 and/or p 53 gene alterations. Int J Cancer 1996, 68 (4): 501−5.
- 78. Kondo S, Barna BP, Kondo Y, Tanaka Y, Casey G, Liu J, Morimura T, Kaakaji R, Peterson JW, Werbel B, Barnett GH. WAF1/CIP1 increases the susceptibility of p 53 non-functional malignant glioma cells to cisplatin-induced apoptosis. Oncogene 1996, 13 (6): 1279−85.
- 79. Li G, Tang L, Zhou X, Tron V, Ho V. Chemotherapy-induced apoptosis in melanoma cells is p 53 dependent. Melanoma Res 1998, 8 (1): 17−23.
- 80. Biagosklonny MV, El-Deiry WS. Acute overexpression of wt p 53 facilitates anticancer drug-induced death of cancer and normal cells. Int J Cancer 1998, 75 (6): 933−940.
- 81. Li R, Sutphin PD, Schwartz D, Matas D, Almog N, Wolkowicz R, Goldginger N, Pei H, Prokocimer M, Rotter V. Mutant p 53 protein interferes with p 53-independent apoptotic pathways. Oncogene 1998, 16 (25): 3269−77.
- 82. Vasey PA, Jones NA, Jenkins S, Dive C, Broun R. Cisplatin, camptothecin, and taxol sensitivities of cells with p 53-associated multidrug resistance. Mol Pharmacol 1996, 50 (6): 1536−40.
- 83. Vikhanskaya F, Clerico L, Valenti M, Stazione NS, Broggini M, Parodi S, Russo P. Mechanism of resistance to cisplatin in a human ovarian-carcinoma cell line selected for resistance to doxorubicin: possible role of p 53. Int J Cancer 1997, 72 (1): 155−9.
- 84. Vaisman A, Varchenko M, Said I, Chaney SG. Cell cycle changes associated with formation of Pt-DNA adducts in human ovarian carcinoma cells with different cisplatin sensitivity. Cytometry 1997, 27 (1): 54−64.
- 85. Siddik ZH, Mims B, Lozano G, Thai G. Independent pathways of p 53 induction by cisplatin and X-rays in a cisplatin-resistant ovarian tumor cell line. Cancer Res 1998, 58 (4): 698−703.
- 86. Ju JF, Banerjee D, Lenz HJ, Danenberg KD, Schmittgen TC, Spreas CP, Schonthal AH, Manno DJ, Hochhauser D, Bertino JR, Danenberg PV. Restoration of wild-type p 53 activity in p 53-null HL-60 cells confers multidrug sensitivity. Clin Cancer Res 1998, 4 (5): 1315−22.
- 87. Fajac A, Da Silva J, Ahomadegbe JC, Rateau JG, Bernaudin JF, Riou G, Benard J. Cisplatin-induced apoptosis and p 53 gene status in a cisplatin-resistant human ovarian carcinoma cell line. Int J Cancer 1996, 86 (1): 67−74.
- 88. Kondo S, Barna BP, Morimura T, Takeuchi J, Yuan J, Akbasak A, Barnett GH. Interleukin-1-beta-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells. Cancer Res 1995, 55 (24): 6166−71.
- 89. De Feudis P, Debernardis D, Beccaglia P, Valenti M, Sire GE, Arzani D, Stanzione S, Parodi S, D`Incalci M, Russo P, Broggini M. DDP-induced cytotoxicity is not influenced by p 53 in nine human ovarian cancer cell lines with different p 53 status. Br J Cancer 1997, 76 (4): 474−9.
- 90. Burger H, Nooter K, Boersma AW, Kortland CJ, Stoter G. Expression of p 53, Bcl-2 and Bax in cisplatin-induced apoptosis in testicular germ cell tumor cell lines. Br J Cancer 1998, 77 (10): 1562−7.
- 91. Ikeguchi M, Tatebe S, Kaibara N, Ito H. Changes in levels of expression of p 53 and the product of the bcl-2 in lines of gastric cancer cells during cisplatin-induced apoptosis. Eur Surg Res 1997, 29 (5), 396−402.
- 92. Pestell KE, Medlow CJ, Titley JC, Kelland LR, Walton MI. Characterisation of the p 53 status, BCL-2 expression and radiation and platinum drug sensitivity of a panel of human ovarian cancer cell lines. Int J Cancer 1998, 77 (6): 913−8.
- 93. Nakata B, Chung KH, Ogawa M, Yanagawa K, Muguruma K, Inoue T, Yamashita Y, Onoda N, Maeda K, Sawada T, Sowa. P 53 protein overexpression as a predictor of the response to themotherapy in gastric cancer. Surg Today 1998, 28 (6): 595−8.
- 94. Petty R, Evans A, Duncan I, Kurbacher C, Cree I. Drug resistance in ovarian cancer — the role of p 53. Payhol Oncol Res 1998, 4 (2): 97−102.
- 95. Simonian PL, Grillot DA, Andrews DW, Leber B, Nunez G. Bax homodimerization is not required for Bax to accelarate chemotherapy-induced cell death. J Biol Chem 1996, 271 (50): 32 073;7.
- 96. Liu JR, Fletcher B, Page C, Hu C, Nunez G Baker V. Bcl-xL is expressed in ovarian carcinoma and modulates chemotherapy-induced apoptosis. Gynecol Oncol 1998, 70 (3), 398−403.
- 97. Miyake H. Hanada N, Nakamura H, Kagawa S, Fujiwara T, Hara I, Eto H, Gohji K, Arakawa S, Kamidono S, Saya H. Overexpression of Bcl-2 in bladder cancer inhibits apoptosis induced by cisplatin and adenoviral-mediated p 53 gebe transfer. Oncogene 1998, 16 (7): 1933;43.
- 98. Minn AJ, Rudin CM, Boise LH, Thompson CB. Expression of bcl-xl can confer a multidrug resistance phenotype. Blood 1995, 86 (5): 1903;10.
- 99. Simonian PL, Grillot AM, Nunez G. Bcl-2 and Bcl-Xl can differentially block chemotherapy induced cell death. Blood 1997, 90 (3): 1208−16.
- 100. Jones NA, Turner J, McIlwrath AJ, Brown R, Dive C. Cisplatinand paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p 53. Mol Pharmacol 1998, 53 (3): 819−26.
- 101. Boersma AW, Nooter K, Burger h, Kortland CJ, Stoter G. Bax upregulation is an early event in cisplatin-induced apoptosis in human testicular germ-cell tumor cell line NT2, as quantitated by flow cytometry. Cytometry 1997, 27 (3): 275−82.
- 102. Lee JU, Hosotani R, Wada H, Doi R, Kosiba T, Fujimoto K, Miyamoto Y, Mori C, Nakamura N, Shiota K, Imamura M. Mechanism of apoptosis induced by cisplatin and VP-16 in PANC-1 cells. Anticancer Res 1997, 17 (5A): 3445−50.
- 103. Houldsworth J, Xiao H, Murty VV, Chen W, Ray B, Reuter VE, Bosl GJ, Chaganti RS. Human male germ cell tumor resistance to cisplatin is linked to TP53 gene mutation. Oncogene 1998, 16 (18): 2345−9.
- 104. Sakahura C, Sweeney EA, Shirahama T, Igarashi Y, Hakomori S, Tsujimoto H, Imanishi T, Ogaki M, Yamazaki J, Hagiwara A, Yamaguchi T, Sawai K, Takahashi T. Overexpression of bax sensitizes breast cancer MCF-7 cells to cisplatin and etoposide. Surg Today 1997, 27 (7): 676−9.
- 105. Kondo S, Shinomura Y, Kanayama S, Higashimoto Y, Kiyohara T, Zushi S, Kitamura S, Ueyama H, Matsuzawa Y. Modulation of apoptosis by endogenous Bcl-Xl expression in MKN-45 human gastric cancer cells. Oncogene 1998, 17(20): 2585−91.
- 106. Nakata B, Muguruma K, Hirakawa K, Chung YS, Yamashita Y, Inoue T, Matsuoka T, Onoda N, Kato Y, SowaM. Predictive value of Bcl-2 and Bax protein expression for chemotherapeutic effect in gastric cancer. Apilot study. Oncol 1998, 55(6): 543−7.
- 107. Boku N, Chin K, Hosokawa K, Ohtsu A, Tajiri H, Yoshida S, Yamao T, Kondo H, Shirao K, Shimada Y, Saito D, Hasebe T, Mukai K, Seki S, Saito H, Johnston PG. Biological markers as a predictor for response and prognosis of unresectable gastric cancer patients treated with 5-fluorouracil and cis-platinum. Clin Cancer Res 1998, 4 (6): 1469−74.
- 108. Herod JJ, Eliopoulos AG, Warwick J, Niedobitek G, Young LS, Kerr DJ. The prognostic significance of bcl-2 and p 53 expression in ovarian carcinoma. Cancer Res 1996, 56 (9): 2178−84.
- 109. Muguruma K, Nakata B, Hirakawa K, Yamashita Y, Onoda N, Inoue T, Matsuoka T, Kato Y, Sowa. P 53 and Bax protein expression as predictor of chemotherapeutic effect in gastric carcinoma. Gan To Kagaku Ryoho 1998, 3: 400−3.
- 110. Ferguson AW, Flatow U, MacDonald NJ, Larminat F, Bohr VA, Steeg PS. Increased sensitivity to cisplatin by nm23-transfected tumor cell lines. Cancer Res 1996; 56: 2931−5.
- 111. Masumoto N, Nakaano S. Cell signalling and CDDP resistance. Gan To Kagaku Ryoho 1997, 24(4): 424−30.
- 112. Demidova NS, Ilynskaya GV, Shiryaeva OA, Chernova OB, Goncharova SA, Kopnin BP. Decreased sensitivity of multidrug-resistant tumor cells to cisplatin is correlated with sorcin gene co-amplification. Neoplasma 1995; 42: 195−201.