Изучение термостабильности и эластичности элементов вторичной структуры ряда белков методом молекулярной динамики
Диссертация
Термостабильность а-спиралей, сформированных сигнальными пептидами, ниже, чем у модельных гомополимерных спиралей типа полиаланина. Дестабилизация вторичной структуры а-спирали начинается локально, в-местах дефектов. Для гомополимерной спирали такими дефектами являются концевые остатки, обладающие большей подвижностью, для гетерополимерной — определенные элементы аминокислотной… Читать ещё >
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