Пространственная и функциональная организация локуса Q22.1 хромосомы человека 16, содержащего LCAT генный кластер
Диссертация
В настоящей работе олигонуклеотидные пробы и бактериальные клоны из локуса хромосомы человека 16q22.1 были использованы для картирования петлевой организации хроматина в районе LCAT генного кластера. Для этого применяли методы, основанные на флуоресцентной гибридизации ДНК in situ с препаратами ДНК-комет и препаратами ядерного гало. Было показано, что протяженный фрагмент геномной ДНК, содержащий… Читать ещё >
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