Стабильность конформационных состояний апомиоглобина и его мутантных форм
Диссертация
В литературе опубликовано много работ, посвященных исследованию структуры промежуточного состояния апомиоглобина. Однако вопрос о том, насколько сильны взаимодействия, удерживающие это состояние, до сих пор остаётся открытым. Для решения этого вопроса во второй части работы проведено исследование вклада ряда аминокислотных остатков в стабильность промежуточного и нативного состояний. Для этого… Читать ещё >
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