Генетические мутации микобактерии туберкулеза, ответственные за резистентность к рифампицину у больных туберкулезом: идентификация и характеристика
Диссертация
В то же время существует и другое мнение, что жизнеспособность бактериальной клетки, устойчивой к 111 И, не только не снижается, но и увеличивается. Инфекционное заболевание, вызванное устойчивыми штаммами, протекает значительно тяжелее, чем обусловленное чувствительными штаммами. A.M. Егоров (2000) пишет, что на примере грамотрицательных бактерий, а затем и других микроорганизмов… Читать ещё >
Список литературы
- Богадельникова И.В., Перельман М. И. Туберкулез на пороге третьеготысячелетия. // Врач. 1997. — № 7 — с. 2−6.
- Генерозов Э.В., Альтшулер М. Л., Говорун В. М. и др. Детекция и характеристика мутаций в гро В гене резистентных к рифампицину клинических штаммов Mycobacterium tuberculosis.// Проблемы туберкулеза. 1999. — № 2. — с.39−42.
- Голубев В.Н. Выявление больных туберкулезом органов дыхания из групп повышенного риска в поликлинике общей лечебно-профилактической сети. // Проблемы туберкулеза. 2000. — № 6 — с. 16−19.
- Егоров A.M. Достижения фундаментальных наук и новые подходы к химиотерапии туберкулеза. // Проблемы туберкулеза. 2000. — № 5. -с. 11−15.
- Иртуганова О.А., Смирнова Н. С., Слогоцкая JT.B. и др. Автоматизированные методы культурального определения Mycobacterium tuberculosis на жидких средах. // Проблемы туберкулеза. 2001. — № З.-с. 53−55.
- Клименко М.Т. Биологические особенности и клиническое значениеполирезистентных Mycobacterium tuberculosis у больных хроническими деструктивными формами туберкулеза легких, // Автореферат диссертации канд. мед. наук. Киев. -1979. — 20 с.
- Клинчева С.А., Николаева Н. П., Гнедой С.Н.и др. Множественное ДНК-зондирование: новый подход к лабораторной диагностике туберкулеза. // В сб. тезисов 4-го Рос. Нац. Конгр. «Человек и лекарство». М. — 1997. — с.191.
- Литвинов В.И., Сельцовский П. П., Сон И.М., Кочеткова Е. Я. Т, ер-кулез в Москве (1999 г.). М. — 2000.- 82 с.
- Майерс Р., Шеффилд В., Кокс Д. Обнаружение единичных нуклео-тидных замен в ДНК: расщепление РНКазой и денатурирующий градиентный гель-электрофорез. // В кн.: Анализ генома. Методы.-М.: Мир.-1990.-с.123−175.
- Мельник В.М. Туберкулез на Украине: состояние, проблемы и прогноз (медико-статистическое исследование). // Проблемы туберкулеза.-2000.-с. 28−31.
- Мишкинис К., Каминскайте А., Пурванецкене Б. Результаты лечения полирезистентного туберкулеза по данным республиканской туберкулезной больницы Сантаришкес. // Проблемы туберкулеза. 2000 — № З.-с. 9−11.
- Патрушев Л.И. Экспрессия генов. // М.: Наука. 2000. — 527 с.
- Приказ МЗ СССР № 558. Об унификации микробиологических методов исследования при туберкулезе. 1978.
- Хоменко А.Г., Голышевская В. И., Корнеев М. В. и др. Распространенность и микробиологическая характеристика штаммов Mycobacterium tuberculosis с множественной лекарственной устойчивостью. // В сб.: Туберкулез. 1999. — № 1. — с. 1−6.
- Чернушенко Е.Ф., Клименко М. Т. Микробиологическая диагностика туберкулеза.// В сб.: Туберкулез. 1999. — № 3. — с. 1−5.
- Шилова М.В. Туберкулез в России в 1999 г.// М. 2000. — 47 с.
- Albert Н., Stupple М., Wilson S. et al. Rifampicin susceptibility results of Mycobacterium tuberculosis cultures in 48 hours using FAST plaque TB-Rif.//Int. J. Tubercle, and LungDis.-1999.-V.3. Suppl.l.-p.130.
- Bakayev V., Bahrmand A., Samar G. CCM analysis of heteroduplexes of rifampin-resistant Mycobacterium tuberculosis. // Int.J. Tubercle, and Lung Dis. 1999. — V.3. — N 9. — Suppl. 1. — p.123.
- Bates J., Stead W., Rado T. Phage type of tubercle bacilli isolated from patients with two or more sites of organ involvement. // Am Rev Respir Dis. 1976. — V. l 14. — p. 353−358.
- Beenhouwer H., Lhiang Z., Jannes G. et al. Rapid detection of rifampicin-resistance in sputum and biopsy specimens from tuberculosis patients by PCR and line probe assay. // Tubercle Lung Dis. -1995. V.76. — p. 425 430.
- Blanchard J.S. Molecular mechanisms of drug resistance in Mycobacterium tuberculosis. // Annu. Rev. Biochem. -1996. V.65. -p.215−39.
- Bloch A., Cauthen G., Onorato I. et al. Nationwide survey of drug-resistant tuberculosis in the United States. // JAMA. 1994. — V.271. -p.665−671.
- Brunello F., Fontana R. Reliability of the MB/BacT system for testing susceptibility of Mycobacterium tuberculosis-complex isolates to antituberculous drugs. // J.Clin.Microbiol. 2000. — V. 38. — p. 872−873.
- Brunello F., Favari F., Fontana R. Comparison of the MB/BacT and BACTEC 460 ТВ systems for recovery of mycobacteria from various clinical specimens. // J.Clin.Microbiol. 1999. — V.37. — p.1206−1209.
- Canetti G., Fox W., Khomenko A. Advances in techniques of testing mycobacterial drug sensitivity, and the use of sensitivity tests in Tuberculosis Control Programmes. // Bull.WHO. 1969. — № 41. — p. 2143.
- Cangelosi G., Brabant W., Britschgi Т., Wallis C. Detection of rifampin-and ciprofloxacin-resistant Mycobacterium tuberculosis by using species-specific assays for precursor rRNA. // Antimicrob. Agents Chemother. -1996.-V.40.- p. 1790−1795.
- Caugant D., Sandven P., Eng J. et al. Detection of rifampin resistance among isolates of Mycobacterium tuberculosis from Mozambique. // Microbial Drug Resistance. 1995. — V.l. — p. 321−326.
- Chakrabarti P. Drug targets and drug resistance in mycobacteria.// Proc.Nat.Acad.Sci. (India, B). 1997. — V.67. — p.169−179.
- Chaulet P., Bonlahbal F., Crosset J. Surveillance of drug resistance for tuberculosis control: why and how?// Int.J.Tubercle. and Lung Dis. 1995. -V.76.-p. 487−492.
- Cohn D., Bustreo F., Raviglione M. Drug-resistant tuberculosis: review of the wordwide situation and the WHO/IUATLD global surveillance project. // Clin.Infect.Dis. 1997. — V.24. — p. 121−130.
- Cooksey R., Crawford J., Jacobs W., Shinnick T. A rapid method for screening antimicrobial agents for activities against a strain of Mycobacterium tuberculosis expressing firefly luciferase. // Antimicrob. Agents Chemother. 1993. — V.37. — p. 1348−1352.
- Cooksey R., Morlock G., Glickman S., Crawford J. Evaluation of a line probe assay kit for characterization of rpoB mutations in rifampin-resistant Mycobacterium tuberculosis isolates from New York City.// J.Clin.Microbiol. 1997. — V.35. — p.1281−1283.
- Cousins D., Williams S., Liebana E. et al. Evaluation of four DNA typing techniques in epidemiological investigations of bovine tuberculosis.// J.Clin.Microbiol. 1998. — V.36. -p.168−178.
- Diaz-Infantes M., Ruiz-Serrano M., Martinez-Sanchez L. et al. Evaluation of the MB/BacT Mycobacterium detection system for susceptibility testing of Mycobacterium tuberculosis.// J.Clin.Microbiol. 2000. — V.38. -p.1988−1989.
- Felmlee Т., Lin Q., Whelen A. et al. Genotypic detection of Mycobacterium tuberculosis rifampin resistance: comparison of single-strand conformation polymorphism and dideoxy fingerprinting.// J.Clin.Microbiol. 1995. — V.33. — p. 1617−1623.
- Foddle R., Losekoot M. Mutation detection by denaturating gradient gel electrophoresis (DGGE).//Hum. Mutat. 1994. — V.3. — p.83−94.
- Gale E., Cundliffe E., Reynolds P. et al. The molecular basis of antibiotic action. //1981. John Wiley & Sons, Inc., New York. p. 131−142.
- Gali N., Dominguez J., McNerney R. et al. Rapid detection of drug resistance in Mycobacterium tuberculosis clinical isolates using micobacteriophage D29. Preliminary study.// Int. J. Tubercle, and Lung Dis. 1999. -V.3. — Suppl.l. — c.129.
- Gillespie S., Baskerville A., Davidson R. et al. The serum rifabutin concentrations in a patient successfully treated for multi-resistant Mycobacterium tuberculosis infection.// J. Antimicrob. Chemother. -1990. V.25. — p.490−491.
- Gingeras Т., Ghandour G., Wang E. et al. Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays.// Genome Research. 1998. — V. 8. -p. 435−448.
- Glavac D., Dean M. Optimization of the single-strand conformation polymorphism (SSCP) technique for detection of point mutations.//Hum.Mutat.-1993. V.2. — p.404−414.
- Go M., Kapur V., Graham D., Musser J. Population genetic analysis of Helicobacter pylori by multilocus enzyme electrophoresis: extensive allelic diversity and recombinational population structure.// J.Baeteriol. -1996. V.178. -p.3934−3938.
- Grompe M. The rapid detection of unknown mutations in nucleic acids.// Nature Genet. 1993. — V.5. — p. l 11−116.
- Hauer В., Serke M., Loddenkemper R. et al. Various polyresistant strains of Mycobacterium tuberculosis in one patient (case report).// Int.J. Tubercle. and Lung Dis. 1999. — V.3. — Suppl. 1. — p. 122.
- Heifets L. Antituberculosis drugs: antimicrobial activity in vitro. In L.B. Heifets (ed.), Drug susceptibility in the chemotherapy of mycobacterial infections, 1st ed. CRC Press, Boca Raton, Fla. 1991. — p. 14−57.
- Heifets L., binder Т., Sanchez T. et al. Two liquid medium systems, Mycobacteria Growth Indicator Tube and MB Redox Tube, for Mycobacterium tuberculosis isolation from sputum specimens.// J.Clin.Microbiol. 2000. — V.38. — p.1227−1230.
- Heym В., Honore N., Truffot-Pernot C. et al. Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study.// Lancet. 1994. — V.344. — p.293−298.
- Huebner R., Castro K. The changing face of tuberculosis.// Ann.Rev.Med. 1995. — V.46. — p. 47−55.
- Hunt J., Roberts G., Stockman L. et al. Detection of a genetic locus encoding resistance to rifampin in mycobacterial cultures and in clinical specimens.// Diagn. Microbiol. Infect. Dis. 1994. — V.18. — p.219−227.
- Iseman M.D. Evolution of drug-resistant tuberculosis: a tale of two species.// Proc.Natl.Acad.Sci. (USA). 1994. — V.91. — p.2428−2429.
- Iseman M., Madsen D. Drug-resistant tuberculosis.// Clin. Chest Med. -1989.-V.10.-p. 341−353.
- Jacobs W., Barleta R., Udani R. et al. Rapid assessment of drug susceptibilities of Mycobacterium tuberculosis by means of luciferase reported phages.// Science. -1993. V.260. — p.819−821.
- Jacobs R.F. Multiple drug-resistant tuberculosis.// Clin Infect Dis 1994. -V.19.-p.l-8.
- Jin D., Gross C. Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance.// J.Mol.Biol. 1988. -V.202. — p.45−58.
- Kochi A.* Vareldris В., Styblo K. Multidrug-resistant tuberculosis and its control.// Res.Mycrobiol. 1993. — V.144. — p.104−110.
- Lambregts-van Weezenbeek C.S.B. Drug-resistant tuberculosis.// Eur Respir Mon. -1997. V.4. — p.298−326.
- Lee S., Tan K., Chew S., Snodgrass I. Multidrug-resistant tuberculosis.// Ann Acad.Med. Singapore. 1995. -V.24. — p.442−446.
- Levin M., Hatflill G. Mycobacterium smegmatis RNA polymerase: DNA supercoiling, action of rifampicin and mechanism of rifampicin resistance.// MoLMicrobiol. 1993. — V.8. — p.277−285.
- Lisitsyn N., Sverdlov E., Moiseyeva E. et al. Mutation to rifampin resistance at the beginning of the RNA polymerase beta subunit gene in Escherichia coli.// Mol.Gen.Genet. 1984. — V.196. — p. 173−174.
- Luna-Herrera J, Reddy M., Gangadharam P. In vitro activity of the benzoxazinorifamycin KRM-1648 against drug-susceptible and multidrug-resistant tubercle bacilli.// Antimicrob Agents Chemother. 1995. — V.38.- p.440−444.
- Maiden M., Bygraves J., Feil E. et al. Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms.// Proc Natl Acad Sci (USA). 1998. — V.95. -p.3140−3145.
- Mankiewicz E., Liivak M. Phage types of Mycobacterium tuberculosis in cultures isolated from Eskimo patients.// Am. Rev. Respir. Dis. 1975. -V.lll. -p.307−312.
- Martin-Casabona N, Xairo Mimo D., Gonzalez T. et al. Rapid method for testing susceptibility of Mycobacterium tuberculosis using DNA probes.// J. Clin Microbiol. 1997. — V.35. — p. 2521−2525.
- Matsiota-Bernard P., Vrioni G., Marinis E. Characterization of гро В mutations in rifampin-resistant clinical MTB isolates from Greece.// J. Clin. Microbiol. 1998. — V.36. — p.20−23.
- McClure W., Cech C. On the mechanism of rifampicin inhibition of RNA synthesis.// J.Biol.Chem. -1978. V.253. — p. 8949−8956.
- Mildvan D. Predictors and outcome of multidrug-resistant tuberculosis.// Clin.Infect.Dis. 1995. — V.21. — p.1245−1252.
- Mitchison D. Drug resistance in mycobacteria.// Brit. Med. Bull. 1984.- V.40. p.84−90.
- Moore M., Onorato I., McGray E., Castro A. Trends in drug-resistant tuberculosis in the United States, 1993−1996.// JAMA. 1997. — V.278. -p.833−837.
- Musser J. Antimicrobial agent resistance in Mycobacteria: molecular genetic insights.// Clin.Microb.Rev. 1995. — V.8. — p. 496−514.
- Nachamkin I., Kang C., Weinstein M. Detection of resistance to isoniazid, rifampin and streptomycin in clinical isolates of Mycobacterium tuberculosis by molecular methods.// Clin.Infect.Dis. 1997. — V.24. -p.894−900.
- Nelson K., Selander R. Evolutionary genetics of the proline permease gene (putP) and the control region of the proline utilization operon in populations of Salmonella and E.coli.// J.Bacteriol. 1992. — V.174. -p.6886−6895.
- Nelson K., Wang F-S., Boyd E., Selander R. Size and sequence polymorphism in the isocitrate dehydrogenase kinase/phosphatase gene (aceK) and flanking regions in Salmonella enterica and E.coil.// Genetics. 1997. -V. 147. — p. 1509−1520.
- Ohno H, Koga H., Kohno S. et al. Relationship between rifampin MICs for and rpoB mutations of Mycobacterium tuberculosis strains isolated in Japan.// Antimicrob Agents Chemother. 1996. — V.40. — p. 1053−1056.
- Orita M., Iwahana H., Kanazawa H., Sekya T. Detection of polymorphism of human DNA by gel electrophoresis as single cell conformation polymorphism.// Proc.Natl.Acad.Sei. USA. -1989. V.86. — p.2766−2770.
- Ovehinnikov Y., Monastyrskaya G., Gubanov V. et al. Primary structure of Escherichia coli RNA polymerase. Nucleotide substitution in the beta subunit gene of the rifampicin resistant rpoB255 mutant.// Mol.Gen.Genet. -1981. -V.184. -p, 536−538.
- Ovchinnikov Y., Monastyrskaya G., Guriev S. et al. RNA polymerase rifampicin resistance mutations in Escherichia coil: sequence changes and dominance.// Mol.Gen.Genet. 1983. — V.190. — p.344−348.
- Ovid Т., Chadee D. The evolution of multidrug resistance of Mycobacterium tuberculosis, Trinidad and Tobago 1998.// Int.J. Tubercle, and Lung Dis. 1999. — V.3- Suppl.l. — p. 120.
- Pretet S., Lebeaut A., Parrot R. et al. Combined chemotherapy including rifabutin for rifamycin and isoniazid resistant pulmonary tuberculosis.// Eur.Respir.J. -1992. V.5. — p.680−684.
- Ramaswamy S., Musser J.M. Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update.// Tubercle Lung Dis. 1998. — V.79. — p.3−29.
- Rattan A., Awdhesh K., Nishat A. Multidrug-resistant Mycobacterium tuberculosis: molecular perspectives.// Emerging Infect. Dis. 1998. — V.4. — p. l95−209.
- Reddy M., Luna-Herrera J, Daneluzzi D, Gangadharum P. Chemotherapeutic activity of benzoxazinorifamycin KRM-1648 against Mycobacterium tuberculosis in C57BL/6 mice.// Tubercle Lung Dis. -1996. V.77. — p. 154−159.
- Rinder H., Dobner P., Feldmann K. Disequilibria in the distribution of rpoB alleles in rifampiein-resistant Mycobacterium tuberculosis isolates from Germany and Sierra Leone.// Microbial Drug Resistance. 1997. -V.3.- p.195−197.
- Rohner P., Ninet В., Metral C. et al. Evaluation of the MB/BacT system and comparison to the BACTEC 460 system and solid media for isolation of mycobacteria from clinical specimens.// J.Clin.Microbiol. 1997. -V.35. -p.3127−3131.
- Rusch-Gerdes S, Domehl C., Nardi G. et al. Multicenter evaluation of the Mycobacteria Growth Indicator Tube for testing susceptibility of
- Mycobacterium tuberculosis to first-line drugs.// J.Clin.Microbiol. 1999. — V.37. — p.45−48.
- Sambrook J., Fritsch E., Maniatis T. Molecular cloning. A laboratory manual // Cold Spring Harbor Laboratory Press. 1989. — Book 1. -p. 1.25−1.28.
- Sebek M. DNA fingerprinting and the contribution to contact investigation.// IntJ.Tubercle. and Lung Dis. 1999. — V.3. — Suppl.l. -p.10−11.
- Shinder D., Cauthen G., Farer L. et al. Drug-resistant tuberculosis.// Amer.Rev.Resp.Dis. 1991. — V.141. — Pt. 1. — p.732−732.
- Shinnik T. Molecular approach to the diagnosis of tuberculosis.// Tuberculosis: pathogenesis, protection and control. 1994. American society for microbiology. Washington. Chapter 30. p. 517−530.
- Taniguchi H., Aramaki H., Nikaido Y. et al. Rifampicin resistance and mutation of the rpoB gene in Mycobacterium tuberculosis.// FEMS Microbiol Lett- 1996. V.144. -p.103−108.
- Teixeira L., Palaci M., Canedo Rocha L. et al. Savety and early bactericidal activity of Rifalazil in patients with pulmonary tuberculosis.// Int. J. Tubercle, and Lung Dis. 1999. — V.3. — Suppl.l. — p.48.
- Telenti A., Imboden P., Marchesi F. et al. Detection of rifampicin-resistanee mutations in Mycobacterium tuberculosis.// Lancet.- 1993. -V.341. -p.647−50.
- Troesch A., Ngueyen H., Miyada C. et al. Mycobacterium species identification and rifampicin-resistant testing with high-dencity DNA probe arrays.// J Clin Microbiol. 1999. — V.37. — p.49−55.
- Van Duin J., Pijnenburg J.E.M., van Ryswoud C. et al. Investigation of cross contamination in Mycobacterium tuberculosis laboratory using IS 6110 DNA fingerprinting.// IntJ.Tubercle. and Lung Dis. 1998. — V.2. -p.425−429.
- Vareldris В., Grosset J., de Kantor I. et al. Drug-resistant tuberculosis: laboratory issues.// Tubercle Lung Dis. -1994. V.75. — p. 1−77.
- Watterson S., Wilson S., Yates M., Drobniewski F. Comparison of three molecular assays for rapid detection of rifampin resistance in Mycobacterium tuberculosis.// J. Clin. Microbiol. 1998. — V.36. -p.1969−1973.
- Whelen A., Felmlee Т., Hunt J. et al. Direct genotypic detection of Mycobacterium tuberculosis Rifampin Resistance in clinical specimens by using single-tube hemi-nested PCR.// J.Clin.Microbiol. 1995. — V.33. -p. 556−561.
- Williams D., Waguerpack C., Eisenach K. et al. Characterization of rifampin resistance in pathogenic mycobacteria.// Antimicrob Agents Chemother. 1994. — V.38. — p.2380−2386.
- Williams D., Limbers C., Spring L. et al. PCR-heteroduplex detection of rifampin-resistant Mycobacterium tuberculosis // In: PCR protocols for emerging infectious diseases. D. Persing (ed.) -19%. p.122−129.
- Williams D., Spring L., Collins L. et al. Contribution of гро В mutations to development of rifampicin cross-resistance in Mycobacterium tuberculosis.// Antimicrob. Agents Chemother. 1998. — V.42. — p. 18 531 857.
- Wilson S., Al-Suwaidi Z., McNerney R. et al. Evaluation of a new rapid bacteriophage-based method for the drug susceptibility testing of Mycobacterium tuberculosis.// Nat.Med. 1997. — V.3. — p.465−468.
- Winder F. Mode of action of the antimycobacterial agents and associated aspects of the molecular biology of the mycobacteria.// In.: The biology of the mycobacteria C. Ratledge and J. Stanford (ed). 1982. -Academic Press, London. — V.l. — p.353−438.
- The world Health Organizaton. Standartization of methods for conducting microbic sensitivity tests. WHO Tech.Rep.Ser.- 1961-N210-p.3−24.
- The World Health Report, 1998// Life in the 21 -st century. A vision for all.-Geneva. 1998. — 54 p.
- Yeh R., Leon A., Agasino C. et al. Stability of Mycobacterium tuberculosis DNA genotypes.// J. Infect. Dis. 1998. — V.177. — p.1107−11.
- Yeh R., Hopewell P., Daley C. Simultaneous infection with two strains of Mycobacterium tuberculosis identified by restriction fragment length polymorphism analysis.// Int.J.Tubercle and Lung Dis. 1999. — V.3. -p.537−539.
- Zwolska Z., Augustynowicz-Kopec E., Klatt M. New automated, non-radiometric system for the culture of mycobacteria MB/BacT.// Int. J. Tubercle, and Lung Dis. -1999. V.3. — Suppl.l. — p. l 12.