Моделирование механизмов реакций ферментативного катализа в активном сайте холинэстераз комбинированными методами квантовой и молекулярной механики
Диссертация
Для решения задач медицины, фармацевтики и биотехнологии необходимы представления о механизмах реакций ферментативного катализа, что предполагает знание элементарных стадий химических превращений в активных центрах белков. Экспериментальные приемы включают исследования структуры белков и их комплексов с аналогами субстратов с использованием методов рентгеноструктурного анализа… Читать ещё >
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