Синтез и исследование свойств конъюгатов олиго-и полинуклеотидов с низкомолекулярными лигандами
Диссертация
Среди широкого спектра научного и практического применения модифицированных олигонуклеотидов в авангарде находятся современные методы анализа ДНК. Для этого применяют конъюгаты олигонуклеотидов с репортерными группами, дающими аналитический сигнал, который позволяет регистрировать комплементарные взаимодействия между олигонуклеотидными зондами и исследуемыми образцами ДНК. Методы повышения… Читать ещё >
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