Супрамолекулярные комплексы нуклеиновых кислот как эффективные системы трансфекции клеток
Диссертация
Влияние присоединения холестерина к PEI на трансфицирующую активность полимера складывается из нескольких факторов. С одной стороны, присутствие остатков холестерина повышает эффективность взаимодействия с биологическими мембранами и, возможно, направляет процесс эндоцитоза полиплексов PEIC/HK по пути рецептор-опосредованного механизма. С другой стороны, уменьшение количества заряженных… Читать ещё >
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