Функциональное состояние сфингомиелинового цикла и активность свободнорадикального окисления липидов в печени крыс при голодании
Диссертация
Голодание без ограничения доступа к питьевой воде является одной из разновидностей стресса, для которой характерны ведущие эндокринно-метаболические перестройки, характерные для состояния функционального напряжения организма. Сегодня интерес к углубленному исследованию биохимии голодания обусловлен, прежде всего, перспективой создания технологий лечебного голодания, основанных на новых принципах… Читать ещё >
Список литературы
- Айрапетян М.Г., Гуляева Н.В.Роль свободнорадикального окисления в механизмах адаптации. //Вестник АМН СССР.-1988.-№ 11.-С. 49−55.
- Бабенко H.A. Регуляция активности сфингомиелиназы и фосфолипазы С плазматических мембран клеток печени крыс разного возраста.// Биохимия 1991.-Т. 56, вып. 2.-е. 367−353.
- Брокерхоф X., Дженсен Р. Липолитические ферменты. М.: Наука, 1978.-400 с.
- Волчегорский И.А., Долгушин И. И., Колесников О. Л., Цейликман В. Э. Роль иммунной системы в выборе даптационной стратегии организма.-Челябинск, 1998.-70 с.
- Волчегорский И.А., Львовская Е. И., Глузмин М. И. и др. Изменение антиокислительной активности сыворотки крови при воспалительной патологии. // Вопр. мед. химии.-1997.-Т. 43, № 4.-е. 233−238.
- Гланц С. Медико-биологическая статистика.-М.: Практика, 1999−193 с.
- Зенков Н.К., Ланкин В. З., Меньщикова Е. Б. Окислительный стресс. Биохимический и патофизиологический аспекты. М.: МАИК. Наука/Интерпериодика, 2001. 343 с.
- Ипатова О.М., Торховсая Т. И., Захарова Т. С., Халилов Э. М. Сфинголипиды и клеточная сигнализация: участие в апоптозе и атерогенезе.//Биохимия.-2006.-Т. 71, вып. 7.-е. 882−893.
- Казначеев В.П., Казначеев C.B. Адаптация и конституция человека.-Новосибирск.-1986.- 119 с.
- Королюк М. А., Иванова Л. И. Определение активности каталазы в сыворотке крови.//Лабораторное дело. 1988.- № 1.- с. 16−18.
- Костюк В.А., Потапович А. И., Лунец Е. Ф. Спектрофотометрическое определение диеновых конъюгатов. // Вопр. мед. химии.-1984.- Т. 30, вып. 4. -с. 125−127.
- Кулинский В.И., Ольховский И. А. Две адаптационные стратегии в неблагоприятных условиях резистентная и толерантная. Роль гормонов и рецепторов. //Успехи соврем, биологии.-1992.-т. 112, вып.5−6.-с.697−714.
- Лушников Е.Ф., Абросимов А. Ю. Гибель клетки (апоптоз). М.: Медицина, 2001.- 192 с.
- Меерсон Ф.З. Адаптация, стресс и профилактика.-М., 1981.-287 с.
- Меерсон Ф.З., Пшенникова М. Г. Адаптация к стрессорным ситуациям и физическим нагрузкам. М.: Медицина, 1988.-256 с.
- Меныцикова Е.Б., Зенков Н. К., Ланкин В. З. и др. Окислительный стресс: патологические состояния и заболевания. Новосибирск: Изд-во Арта, 2008. 284 с.
- Меныцикова Е.Б., Ланкин В. З., Зенков Н. К., Бондарь И. А., Круговых Н. Ф., Труфакин В. А. Окислительный стресс. Прооксиданты и антиоксиданты. М.: Фирма «Слово», 2006. — 553 с.
- Москалева Е.Ю., Северин С. Е. Возможные механизмы адаптации клетки к повреждениям, индуцирующим программируемую гибель. Связь с патологией //Патол. физиол. 2006. (2): 2−16.
- Октябрьский О.Н., Смирнова Г. В. Редокс-регуляция клеточных функций.//Биохмиия.-2007.-Т. 72, вып. 2.-С. 158−174.
- Остерман Л.А. Хроматография белков и нуклеиновых кислот.-М.: Наука, 1985.-536 с.
- Панин Л.Е. Энергетические аспекты адаптации. М.-Л.: Медицина, 1978. 170 с
- Панин Л.Е., Соколов В. П. Психосоматические взаимоотношения при хроническом эмоциональном напряжении. Новосибирск: Наука, Сибирское отделение, 1981. 238 с.
- Панин JI.E., Кузьменко Д. И. Роль питания в изменении энергетического обмена в условиях стресса.//Вопр. Питания.- 1982.-№. З.-С. 15−18.
- Панин Л.Е. Биохимические механизмы стресса.-Новосибирск: Наука, 1983.- 234 с.
- Панин Л.Е., Кузьменко Д. И., Колпаков А. Р. Роль липопротеидов крови в адаптивной перестройке митохондриального аппарата печени крыс. //Бюлл. эксперим. биологии и медицины.-1982.-Т. 94, № 9.- С. 50−52.
- Панин Л.Е., Кузьменко Д. И., Колпаков А. Р. Влияние апобелков липопротеидов крови на функциональное состояние митохондрий печени крыс. //Вопр. мед. химии.-1983.-Т. 29, вып. З.-С. 92−95.
- Практическая химия белка./под ред. А. Дарбре. М.: Мир, 1989.-623 с.
- Розен В.Б. Основы эндокринологии.-М.: Высшая школа, 1984.-336 с.
- Самуилов В.Д., Олескин A.B., Лагунова Е. М. Программируемая клеточная смерть. //Биохимия. 2000.- Т. 65, № 8, — с. 1029−1046.
- Стальная И.Д., Гаришвили Т. Г. Современные методы в биохимии.- М.: Медицина, 1978.-с. 66−68.
- Строев Е.А., Макарова В. Г. Практикум по биологической химии.-М.: Высшая школа, 1986.-231 с.
- Структурные основы адаптации и компенсации нарушенных функций: Руководство. /Под ред. Д. С. Саркисова.-М., 1987.-448 с.
- Турпаев К.Т. Активные формы кислорода и регуляция экспрессии генов. //Биохимия.-2002.-Том 61.-с.339−352.
- Шведова A.A., Полянский Н. Б. Метод определения конъюгатов гидроперекисей липидов в экстрактах тканей. //Исследованиесинтетических и природных антиоксидантов in vitro и in vivo.- М.: Наука, 1992.-С.74−76.
- Швембергер И.Н., Гинкул Л. Б. Апоптоз: роль в нормальном онтогенезе и патологии. //Вопр. онкологии.-2002.-Т. 48, № 2.-С. 153−158.
- Яковлев Г. М., Новиков B.C., Хавинсон В. Х. Резистентность, стресс, регуляция.-Л.:Наука.-1990.-237 с.
- Ahima R.S., Prabakaran D., Mantzoros С., Qu D., Lowell В., Maratos-Flier E., et al. Role of leptin in the neuroendocrine response to fasting.//Nature.-1996.-Vol. 382.-P. 250−252.
- Ahima RS. Leptin and the neuroendocrinology of fasting.//Front. Horm.
- Albanes D. Total calories, body weight, and tumor incidence in mice.//Cancer Res.- 1987.-Vol. 47.-N 8.-P. 1987−1992.
- Alessenko A.V. The role of sphingomyelin cycle metabolites in transduction of signals of cell prolipheration, differentiation and death.//Membr. Cell. Biol.-2000.-Vol.13.-P. 303−320.
- Alnemri E. S., Livingston D. J., Nicholson D. W., Salvesen G., Thornberry N. A., Wong W. W., Yuan J. Human ICE/CED-3 protease nomenclature.//Cell.-1996.-Vol. 87.-P. 171−178.
- Andriamampandry M.D., Bnouham M., Michard D., Gutbier G., Le Maho Y., Leray C. Food deprivation modifies fatty acid partitioning and beta-oxidation capacity in rat liver.// J. Nutr.-1996.-Vol. 126.-P. 2020−2027.
- Andrieu-Abadie N., Gouaze V., Salvayre R., Levade T. Ceramide in apoptosis signalling: relationship with oxidative stress.// Free Radical Biology and Medicine.-2001.-Vol. 31, No. 6.-P. 717−728
- Andrieu-Abadie N., Levade T. Sphingomyelin hydrolysis during apoptosis. //Biochim. Biophys. Acta.-2002.-Vol. 1585, N 2−3.-P. 126−134.
- Asayama K., Hayashibe H., Dobashi K. et al., Antioxidant enzyme status and lipid peroxidation in various tissues of diabetic and starved rats. //Diabetes Res.-1989.-Vol. 12.-P. 85−92.
- Auchon D., Jiang X., Morgan D.G., Heuser J.E., Wang X., Akey C.W. Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.//Mol. Cell.-2002.-Vol. 9.-P. 423−432.
- Auge N., Negre-Salvayre A., Salvayre R., Levade T. Sphingomyelin metabolites in vascular cell signaling and atherogenesis. //Prog. Lipid Res.-2000.-Vol. 39.-P. 207−229.
- Ayasolla K., Khan M., Singh A. K., Singh I. Inflammatory mediator and beta-amyloid (25−35)-induced ceramide generation and iNOS expression are inhibited by vitamin E. //Free Radic. Biol. Med.-2004.-Vol. 37.-P. 325−338.
- Barb C.R., Hausman G.J., Houseknecht K.L. Biology of leptin in the pig.// Domest. Anim. Endocrinol.- 2001.-Vol. 21.-P. 297−317.
- Bartke N., Hannun Y.A. Bioactive sphingolipids: metabolism and function. //J. Lipid Res.-2009.-Vol. 50.-P. S91-S96.
- Basu S., Kolesnick R. Stress signals for apoptosis: ceramide and c-Jun kinase.//Oncogene.-1998.-Vol. 17.-P. 3277−3285.
- Bauer M., Hamm A.C., Bonaus M., Jacob A., Jaekel J., Schorle H., Pankratz M. J., Katzenberger J.D. Starvation response in mouse liver shows strong correlation with life-span-prolonging rocesses. //Physiol. Genomics.-2004.-Vol. 17.-P. 230−244.
- Belkhou R., Cherel Y., Heitz A., Robin J.-P., Le Maho Y. Energy contribution of proteins and lipids during prolonged fasting in the rat. //Nutrition Research.-1991.-Vol. 11, N4.-P. 365−374.
- Bernard S.F., Mioskowski E., Groscolas R. Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin.//Am. J. Physiol. Regul. Integr. Comp. Physiol.- 2002.-Vol. 283.-P. R144-R152.
- Bertile F., Le Maho Y., Raclot T. Coordinate upregulation of proteolytic-related genes in rat muscle during late fasting.//Biochem. Biophys. Res. Commun.-2003.-Vol. 311.-P. 929−34.
- Boden G., Chen X., Mozzoli M., Ryan I. Effect of fasting on serum leptin in normal human subjects. //J. Clin. Endocrinol. Metab.-1996.-Vol. 81.-P. 34 193 423.
- Boelen A., Wiersinga W.M., Fliers E. Fasting-induced changes in the hypothalamus-pituitary-thyroid axis.// Thyroid.-2008.-Vol. 18, N 2.-P. 123−129.
- Bond J. S., Offerman M. K. Initial events in the degradation of soluble cellular enzymes: factors affecting the stability and proteolytic susceptibility of fructose-1,6-biphosphate aldolase. //Acta Biol. Med. Germ.-1981.-Vol. 40.-P. 1365−1374.
- Bourbon N.A., Yun J., Kester M. Ceramide directly activates protein kinase C ^ to regulate a stress-activated protein kinase signaling complex. //J. Biol. Chem.- 2000.-Vol. 275.-P. 35 617−23.
- Braissant O., Foufelle F., Scotto C., Dauca M., Wahli W. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. //Endocrinology.1996.-Vol. 137.-P. 354−366.
- Brenner B., Koppenhoefer U., Weinstock C., Linderkamp O., Lang F., Gulbins E. Fas- or ceramide-induced apoptosis is mediated by a Rac 1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153. //J. Biol. Chem.1997.-Vol. 272.-P. 22 173−81.
- Brigelius R. Glutathione oxidation and activation of pentose phosphate cycle during hydroperoxide metabolism. A comparison of livers from fed and fasted rats.// Hoppe Seyler’s Z. Physiol. Chem.-1983.-Vol. 364.-P. 989−996.
- Broker L.E., Kruyt F.A., Giaccone G. Cell death independent of caspases: a review.//Clin. Cancer Res.-2005.-Vol. 11.-P. 3155−62.
- Cecconi F., Gouss P. Apafl in developmental apoptosis and cancer: how many ways to die? //Cell. Mol. Life Sci.-2001.-Vol. 58.-P. 1688- 1697.
- Chan J.L., Heist K., DePaoli A.M., Veldhuis J.D., Mantzoros Ch.S. The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men.//J. Clin. In vest.-2003.-Vol. 11 l.-P. 1409−1421.
- Chandoga J. Properties and biogenesis of peroxisomes.// Bratisl. Lek. Listy.-1994.-Vol. 95.-P -543−557.
- Chandra J., Samali A., Orrenius S. Triggering and modulation of apoptosis by oxidative stress//Free Radical Biology & Medicineio-2000.-Vol. 29, N 3A.-P. 323−333.
- Cherel Y., Le Maho Y. Refeeding after the late increase in nitrogen excretion during prolonged fasting in the rat.//Physiol. Behav.-1991.-Vol. 50.-P. 345−349.
- Chow C. K. Nutritional influence on cellular antioxidant defense systems. //Am. J. Clin. Nutr.-1979.-Vol., 32.-P. 1066−1081.
- Clarke Ch. J., Guthrie J. M., Hannun Y.A. Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-a involves protein kinase C in lung epithelial cells.//Mol. Pharmacol.-2008.-Vol. 74.-P. 1022−1032.
- Cock, J.G., Tepper, A.D., de Vries, E., van Blitterswijk, W.J., Borst, J. CD95 (Fas:APO-l) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase.//.!. Biol. Chem.- 1998.-Vol. 273.-P. 75 607 565.
- Cohen G.M. Caspases: the executioners of apoptosis. //Biochem. J.-1997.-Vol. 326.-P. 1 -16.
- Colombaioni L., Garcia-Gil M. Sphingolipid metabolites in neural signalling and function. // Brain Research Reviews.-2004.-Vol. 46.-P. 328- 355.
- Cortright RN, Koves TR.-Sex differences in substrate metabolism and energy homeostasis. //Can J Appl Physiol.-2000.-Vol.25, N 4.-P. 288−311.
- Cusin I., Sainsbury A., Rohner-Jeanrenaud F. The ob gene and insulin: a relationship leading to clues to the understanding of obesity .//Diabetes. -1995.-Vol. 44.-P. 1467−1470.
- Darras, V.M., Mol, K.A., Van der Geyten, S., KuEhn, E.R. Control of peripheral thyroid hormone levels by activating and inactivating deiodinases. //Trends Comp. Endocrinol. Neurobiol.-1998.-Vol. 839.-P. 80−86.
- Del Peso L., Gonzalez-Garcia M., Page C., Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. //Science.-1997.-Vol. 278.-P. 687−9.
- Desvergne B., Upenberg A., Devchand P.R., Wahli W. The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signalling.// J. Steroid Biochem. Mol. Biol.- 1998.-Vol. 65.-P. 65−74.
- Di Simplicio P., Rossi R., Falcinelli S., Ceserani R., Formento M. L. Antioxidants status in various tissue of the mouse after fasting and swimming. //Eur. J. Appl. Physiol.-1997.-Vol. 76.-P. 302−307.
- Dobrowsky R.T. and Hannun Y.A. Ceramide stimulates a cytosolic protein phosphatase.//J Biol Chem.-1992.-Vol. 267.-P. 5048−51.
- Dobrowsky, R. T. and Hannun, Y. A. Ceramideactivated protein phosphatase: partial purification and relationship to protein phosphatase 2A. //Adv. Lipid Res. 1993.Vol. 25.-P. 91 -104.
- Dobrzyn A., Gorski J. Ceramide and sphingomyelins in skeletal muscles of the rat: content and composition. Effect of prolonged exercise. //Am. J. Physiol. Endocrinol.-2002.-Vol. 282.-P. E277 E285.
- Doornbos R.P., Theelen M., van der Hoeven P.C., van Blitterswijk W.J., Verkleij A.J., van Bergen en Henegouwen P.M. Protein kinase C zeta is anegative regulator of protein kinase B activity. //J. Biol. Chem.-1999.-Vol. 274.-P. 8589−96.
- Douvon I., Steingart D.E. Effect of obesity and starvation on thyroid hormone, growth hormone, and Cortisol secretion.// Endocrinol. Metab. Clin. North. Am.-2002.-Vol. 31.-P. 173- 189.
- Droge W. Free radicals in the physiological control of cell function. //Physiol. Rev.-2002.-Vol.82, N l.-P. 47−95.
- Du C., Fang M., Li Y., et al. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.// Cell.-2000.-Vol. 102.-P. 33−42.
- Duncomb W. The colorimetric micro-determination of non-esterified fatty acid in plasma. // Clin. Chim. Acta.- 1964.-Vol. 9, N l.-P. 122−131.
- Eaton S. Control of mitochondrial beta-oxidation flux.//Prog. Lipid Res.-2002.-Vol. 41.-P. 197−239.
- Escriva H., Delaunay F., Laudet V. Ligand binding, and nuclear receptor evolution. //Bioessays.-2000.-Vol. 22.-P. 717−727.
- Faggioni R., Moser A., Feingold K.R., Grunfeld C. Reduced leptin levels in starvation increase susceptibility to endotoxic shock.//Am. J. Pathology.-2000.-Vol. 150.-N 5.-P.1781−1787.
- Farooqi I.S., et al. Effects of recombinant leptin therapy in a child with congenital leptin deficiency.//N. Engl. J. Med.-1999.-Vol. 341.-P. 879−884.
- Feinstein R., Kanety H., Papa M., Lunenfeld B., Karasik A. Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin-receptor and its substrates. //J. Biol. Chem.-1993.-Vol. 268.-P. 26 055−26 058.
- Ferrannini E., Galvan A.Q., Gastaldelli A. et al., Insulin: new roles for an ancient hormone. //Eur J Clin Invest.-1999.-Vol. 29.-P. 842−852.
- Flier J.S. Clinical review 94: what’s in a name? In search of leptin’s physiologic role. //J. Clin. Endocrinol. Metab.-1998.-Vol. 83.-P. 1407−1413.
- Folch J., Lees M., Sloane-Stanley G. H. A simple method for the isolation and purification of total lipids from animal tissues. //J. Biol. Chem.-1957.-Vol. 226.-P. 497−502.
- Fontana L., Klein S. Aging, adiposity, and calorie restriction.// JAMA.-2007.-Vol. 297.-P. 986−994.
- Forman B.M., Chen J., Evans R.M. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferatoractivated receptors alpha and delta. //Proc. Natl. Acad. Sci. USA. -1997.-Vol. 94.-P. 43 124 317.
- Foster D.W. The role of the carnitine system in human metabolism. //Ann. NY Acad. Sci.-2004.-Vo.l 1033.-P. 1−16.
- Fried S., Zechner R. Cachectin tumor necrosis factor decreases human adipose-tissue lipoprotein-lipase messenger-RNA levels, synthesis, and activity.// J. Lipid Res.-1989.-Vol. 30.-P. 1917−1923.
- Futerman A.H., Hannun Y.A. The complex life of simple sphingolipids. //EMBO reports.- 2004.-Vol 5, N 8.-P. 777−782.
- Gasbarrini A., Borle A.B., Farghali H. et al: Fasting enhances the effects of anoxia on ATP, Cai2+ and cell injury in isolated rat hepatocytes. //Biochim. Biophys. Acta.-1993.-Vol. 1178.-P. 9−19.
- Gerstenblith G./Cardiovascular aging: what we can learn from caloric restriction.//J. Am. Coll. Cardiol.-2006.-Vol. 47.-P. 403−404.
- Getty-Kaushik L., Richard A.M., Corkey B.E. Free fatty acid regulation of glucose-dependent intrinsic oscillatory lipolysis in perifused isolated rat adipocytes. //Diabetes.-2005.-Vol. 54.-P. 629 -637.
- Goodman M.N., Larsen P.R., Kaplan M.M., Aoki T.T., Young V.R., Ruderman N.B. Starvation in the rat. II. Effect of age and obesity on protein sparing and fuel metabolism.//Am. J. Physiol.-1980Vol. 239.-P. E277−86.
- Grisham M. B., Jourd’Heuil D., Wink D. A. Nitric oxide: I. Physiological chemistry of nitric oxide and its metabolites amplications in inflammation. //Am. J. Physiol.- 1999.-Vol. 276.-P. G315-G321.
- Gronemeyer H., Laudet V. Transcription factors 3: nuclear receptors. //Protein Profile.- 1995.-Vol. 2.-P. 1173−1308.
- Gulbins E. Regulation of death receptor signaling and apoptosis by ceramide.//Pharmacological Research.-2003.-Vol. 47.-P. 393−399.
- Gulbins E., Li P.L. Physiological and pathophysiological aspects of ceramide.//Am. J. Physiol. Regul. Integr. Comp. Physiol.-2006.-Vol. 290.-P. R11-R26.
- Haendeler J., Weiland U., Zeiher A. M., Dimmeler S. Effects of redox-related congeners of NO on apoptosis and caspase-3 activity. //Nitric Oxide.-1997.-Vol. L-P. 282−293.
- Haldar S., Basu A., Croce C.M. Serine-70 is one of the critical sites for drug-induced Bcl2 phosphorylation in cancer cells. //Cancer Res.-1998.-Vol. 58.-P. 1609−15.
- Hampton M. B., Orrenius S. Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis. //FEBS Lett.-1997.-Vol. 414.-P. 552−556.
- Hannun Y. A. Functions of ceramide in coordinating cellular-responses to stress.// Science.-1996.-Vol. 274.-P. 1855−1859.
- Hannun Y. A. The Sphingomyelin Cycle and the Second Messenger Function of ceramide. // J. Biol. Chem.-1994.-Vol. 269, N. 5.-P. 3125−3128.
- Hannun Y.A. The sphingomyelin cycle and the second messenger function of ceramide.//J. Biol. Chem.-1994.-Vol. 269.-P.31 25−3128.
- Hannun Y.A., Bell R.M. Regulation of protein kinase C by sphingosine and lysosphingolipids.//Clin. Chim. Acta.- 1989.-Vol. 185.-P. 333−345.
- Hannun Y.A., Luberto Ch. Ceramide in the eukaryotic stress response.// Trends in Cell Biology.-2000.-Vol. 10.-P. 73−80.
- Hannun Y.A., Obeid L.M. Ceramide: an intracellular signal for apoptosis // Trends Biochem. Sci.-1995.-Vol. 20.-P. 73−77.
- Hannun Y.A., Obeid L.M. The ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind. //J. Biol. Chem.-2002.-Vol. 277.-P. 25 847−25 850.
- Hannun, Y. A., Loomis C. R., Merrill A. H., Jr., Bell R. M. Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in Vitro and in human platelets. // J. Biol. Chem-. 1986.-Vol. 261.-P. 12 604−12 609.
- Hauner H., Petruschke T., Russ M., Rohrig K., Eckel J. Effects of tumor necrosis factor-alpha (TNF-alpha) on glucose transport and lipid metabolism in newly-differentiated fat cells in culture. //Diabetologia.-1995.-Vol. 38.-P. 764 771.
- Hawkins J.M., Jones W.E., Bonner F.W., Gibson G.G. //Drug Metab. Rev.-1987.-Vol. 18.-P. 441−551.
- Hebestreit H., Dibbert B., Balatti I., Braun D., Schapowal A., Blaser K., Simon H. U. Disruption of fas receptor signaling by nitric oxide in eosinophils.//J. Exp. Med.-1998.-Vol. 187.-P. 415125.
- Hegardt F.G. Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: a control enzyme in ketogenesis.//Biochem. J.-1999.-Vol. 338.-P. 569−582.
- Helge J.W., Dobrzyn A., Saltin B., Gorski J. Exercise and training effects on ceramide metabolism in hman skeletal muscle.//Exp. Physiol.-2004.-Vol. 89, N l.-P. 119−127.
- Hengartner M.O. The biochemistry of apoptosis.// Nature.-2000.-Vol. 407.-P. 770−776.
- Herrlich P., Bohmer F.D. Redox-regulation of signal transduction in mammalian cells.//Biochem. Pharmacol.-2000.-Vol. 59.-P. 35−41.
- Hokin, L. E., Hokin M. R., Mathison D. Phosphatidic acid phosphatase in the erythrocyte membrane.//Biochim Biophys Acta.-1964.-Vol. 67.-P. 485−497.
- Hotamisligil G., Arner P., Caro J., Atkinson R., Spiegelman B. Increased adipose tissue expression of tumor necrosis factor-a in human obesity and insulin resistance. //J. Clin. Invest.-1995.-Vol. 95.-P. 2409−2415.
- Hotamisligil G., Shargill N., Speigelman B. Adipose expression of tumor necrosis factor-?: direct role in obesity-linked insulin resistance. //Science.-1993.-Vol. 259.-P. 87−91.
- Houseknecht K.L., Baile C.A., Matteri R.L., Spurlock M.E. The biology of leptin: a review. //J. Anim. Sci.-1998.-Vol. 76.-P.-1404−1420.
- Houseknecht K.L., Portocarrero C.P. Leptin and its receptors: regulators of whole-body energy homeostasis.// Domest. Anim. Endocrinol.-1998.-Vol. 15.-P. 457−75.
- Hulbert A.J., Pamplona R., Buffenstein R., Buttemer W.A./Life and death: metabolic rate, membrane composition, and life span of animals. // Physiol Rev.-2007.-Vol. 87.-P. 1175−1213.
- Huwiler A., Kolter T., Pfeilschifter J. and Sandhoff K. Physiology and pathophysiology of sphingolipid metabolism and signaling.// Biochim. Biophys. Acta.-2000.-Vol. 1485.-P. 63−99.
- Igarashi T., Satoh T., Ueno K., Kitagawa H. Species differences in glutathione level and glutathione related enzyme activities in rats, mice, guinea pigs, and hamsters. //J. Pharmacobiodyn.- 1983.-Vol. 6.-P. 941−949.
- Inagi R., Miyata T. Oxidative protein damage with carbohydrates and lipids in uremia: 'Carbonyl stress'. //Blood. Purif.-1999.-Vol. 17.-P. 95−98.
- Isaacs J. T., Binkley F. Cyclic AMP-dependent control of the rat hepatic glutathione disulfide-sulfhydryl ratio. //Biochim. Biophys. Acta.-1977.-Vol. 498.-P. 29−38.
- Isaacs J. T., Binkley F. Gtutathione dependent control of protein disulfide-sulfhydryl content by subcellular fractions of hepatic tissue. //Biochim. Biophys. Acta.- 1977.-Vol. 497.-P. 192−204.
- Ishii H., Horie S., Suga T. J. Physiological role of peroxisomal b-oxidation in liver of fasted rats. //J. Biochem. (Tokyo).-I980.-Vol. 87.-P. 1855−1858.
- Jarvis W.D., Fornari F.A., Browning J.L., Gewirtz D.A., Kolesnick R.N., Grant S. Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells.//J. Biol. Chem.-1994.-Vol. 269.-P. 31 685−92.
- Jiang C., Ting A.T., Seed, B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. //Nature.-1998.-Vol. 391.- P. 79−82.
- Johnston D.G., Pernet A., McCulloch A., Blesa-Malpica G., Burrin G.M., Alberti K.G. Some hormonal influences on glucose and ketone body metabolism in normal human subjects.//Ciba Found Symp.-1982.-Vol. 87.-P. 168 -91.
- Joseph C.K., Byun H.S., Bittman R., Kolesnick R.N. Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directed. //J. Biol. Chem.-1993.Vol. 268.-P. 20 002−20 006.
- Kennedy G.C. The role of depot fat in the hypothalamic control of food intake in the rat.//Proc. Royal. Soc.- 1953.-Vol. 140.-P. 578−592.
- Kerckaert I., Van den Branden C., Roels F. Fasting increases hepatic H202 production in vivo. //Arch. Int. Physiol. Biochim.- 1982.-Vol. 90.-P. B124-B126.
- Kern P., Saghizadeh M., Ong J., Bosch R., Deem R., Simsolo R. The expression of tumor necrosis factor in human adipose tissue. //J. Clin. Invest.-1995.-Vol. 95.-P. 2111−2119.
- Kerndt P.R., Naughton J.L., Driscoll Ch.E., Loxterkamp D.A. Fasting: The history, pathophysiology and complications.// West. J. Med.-1982.-N 137.-P. 379−399.
- Kersten S., Seydoux J., Peters J.M., Gonzalez F.J., Desvergne B., Wahli 1 W. Peroxisome proliferator-activated receptor ?? mediates the adaptive response to fasting. //J. Clin. Invest.-1999.-Vol. 103.-P. 1489−1498.
- Kiechle L., Zhang X. Apoptosis: biochemical aspects and clinical implications.// Clin. Chim acta.-2002.-Vol. 326.-P.27−45.
- Kim J.B., Sarraf P., Wright M., Yao K.M., Mueller E., Solanes G., Lowell B.B., Spiegelman B.M. Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.// J. Clin. Invest.-1998.-Vol. 101.-P. 1−9.
- Kim Y. M., Talanian R. V., Billiar T. R. Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. //J. Biol. Chem.-1997.-Vol. 272.-P. 31 138−31 148.
- Kim Y. M., Talanian R. V., Li J., Billiar T. R. Nitric oxide prevents IL-lbeta and IFN-gamma-inducing factor (IL-18) release from macrophages by inhibiting caspase-1 (IL-1 beta-converting enzyme). //J. Immunol.-1998.-Vol. 161.-P. 41 224 128.
- Kishikawa K, Chalfant C.E., Perry D.K., Bielawska A, Hannun Y.A. Phosphatidic acid is a potent and selective inhibitor of protein phosphatase 1 and an inhibitor of ceramide-mediated responses. //J. Biol. Chem.- 1999.-Vol. 274.-P.21 335−41.
- Kolesnick R. The therapeutic potential of modulating the ceramide/sphingomyelin pathway. //J. Clin. Invest.-2002.Vol. 110 (l).-P. 3−8.
- Kolesnick R., Kronke M. Regulation of ceramide production and apoptosis. //Annu. Rev. Physiol.-1998.-Vol. 60.-P. 643−665.
- Kolesnick, R. N., Haimovitz-Friedman A., Fuks Z. The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation. // Biochem. Cell Biol.-1994.-Vol. 72.-P. 471−474.
- Kondrup J., Lazarow P.B. Flux of palmitate through the peroxisomal and mitochondrial beta-oxidation systems in isolated rat hepatocytes. //Biochim. Biophys. Acta.-1985.-Vol. 835.-P. 147−153.
- Kono Y., Fridovich I. Superoxide radical inhibits catalase. //J. Biol. Chem.-1982.-Vol. 257.-P. 5751−5754.
- Kooij A. A re-evaluation of the tissue distribution and physiology of xanthine oxidoreductase. //Histochem. J.-1994.-Vol. 26.-P. 889−915.
- Koubi H.E., Robin J.P., Dewasmes G., Le Maho Y., Frutoso J., Minaire Y. Fasting-induced rise in locomotor activity in rats coincides with increased protein utilization.//Physiol. Behav.-1991.-Vol. 50.-P. 337−343.
- Krammer P.H. CD95's deadly mission in the immune system. // Nature.-2000.-Vol. 407 -P. 789−795.
- Kroetz D.L., Yook P., Costeti P., Bianchii P., Pineaui T. Peroxisome proliferator-activated receptor a controls the hepatic CYP4A induction adaptiveresponse to starvation and diabetes.//J. Biol. Chem.-1998.-Vol. 273, No. 47.-P. 31 581−31 589.
- Kronke M. The mode of ceramide action: the alkyl chain protrusion model.// Cytokine Growth Factor Rev.-1997.-Vol. 8.-P. 103−107.
- Lafontan M., Barbe P., Galitzky J., Tavernier G., Langin D., Carpene C., et al. Adrenergic regulation of adipocyte metabolism. //Hum. Reprod.-1997.-Vol. 12.-P. 6−20.
- Lammi-Keefe C.J., Swan P.B., Hegarty P.V.J. Effect of level of dietary protein and total or partial starvation on catalase and superoxide dismutase activity in cardiac and skeletal muscles in young rats. //J. Nutr.-1984.-Vol. 114.-P. 2235−2240.
- Large V., Arner P. Regulation lipolysi in humans. Pathophysiological modulation in obesity, diabetes and hyperlipidaemia. //Diabetes and metabolism.-1998.-Vol. 24.-P. 409−418.
- Lash L.H., Hagen T.M., Jones D.P. Exogenous glutathione protects intestinal epithelial cells from oxidative injury. //Proc.Natl. Acad. Sci. U.S.A.-1986.-Vol. 83.-P. 4641−4645.
- Lau K. H. W., Thomas J. A. Specific mixed disulfide formation with purified bovine cardiac glycogen synthetase I and glutathione. //J. Biol. Chem.-1983.-Vol. 258.-P. 2321−2326.
- Lauterburg B. H., Mitchell J. R. Regulation of hepatic glutathione turnover in rats in vivo and evidence for kinetic homogeneity of the hepatic glutathione pool. //J. Clin. Invest.- 1981.-Vol. 67.-P. 1415−1424.
- Lauterburg B. H., Mitchell J. R. Regulation of hepatic glutathione turnover in rats in vivo and evidence for kinetic homogeneity of the hepatic glutathione pool. //J. Clin. Invest.- 1981.-Vol. 67.-P. 1415−1424.
- Lazarow P. B. Lipoproteins and Coronary Heart Disease: New Aspects in the Diagnosis and Therapy of Disorders of Lipid Metabolism (Schettler, P. D., Greten, G. & Land, H., eds.).-1980.-P. 96−100, Gerhard Witzstrock, New York.
- Lee J. T., Xu J., Lee J. M., Ku G., Han X., Yang D. I., Chen S., Hsu C. Y. Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway.//J. Cell Biol.-2004.-Vol. 164.-P. 123−131.
- Leist M., Single B., Naumann H., Fava E., Simon B., Nicotera P. Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis. //Exp. Cell Res.-1999.-Vol. 249.-P. 396−403.
- Lemberger T., et al. Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm. //J. Biol. Chem.-1996.-Vol. 279.-P. 1764−1769.
- Lin J., Barb C.R., Matteri R.L., Kraeling R.R., Chen X., Meinersmann R.J., Rampacek G.B. Long form leptin receptor mRNA expression in the brain, pituitary, and other tissues in the pig. //Domest. Anim. Endocrinol.-2000.-Vol. 19.-P. 53−61.
- Lipton S. A. Janus faces of NFkB: neurodestruction versus neuroprotection. //Nat. Med.- 1997.-Vol. 3.-P. 20−22.
- Little C., O’Brien P. J. An intracellular GSH-peroxidase with a lipid peroxide substrate. //Biochem. Biophys. Res. Commun.-1968.-Vol. 31.-P. 145 150.
- Liu B., Hannun Y. A. Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione. //J. Biol. Chem.-1997.-Vol. 272.-P. 1 628 116 287.
- Lopes-Cardozo M., Mulder I., van Vugt F., Hermans P.G., van den Bergh S.G., Klazinga W., et al. Aspects of ketogenesis: control and mechanism of ketone-body formation in isolated rat-liver mitochondria. //Mol. Cell. Biochem.-1975.-Vol. 9.-P. 155−173.
- Lu, M.H., Warbritton, A., Tang, N., Bucci, T.J., 2002. Dietary restriction alters cell proliferation in rats: an immunohistochemical study by labeling proliferating cell nuclear antigen. //Mech. Ageing Dev. 123, 391−400.
- Mangelsdorf D.J., Thummel C., Beato M., Herrlich P., Schultz G., Umesono K. The nuclear receptor superfamily: the second decade. //Cell.-1995.-Vol. 83.-P. 835−839.
- Mannaerts G. P., Debeer L. J., Thomas J., De Schepper P. J. Mitochondrial and peroxisomal fatty acid oxidation in liver homogenates and isolated hepatocytes from control and clofibrate-treated rats. //J. Biol. Chem.-1979.-Vol. 254.-P. 4585−4595.
- Mannaerts G.P., Van Valdhoven P.P., Casteels M. Peroxisomal lipid degradation via beta- and alpha-oxidation in mammals. //Cell. Biochem. Biophys.-2000.-Vol. 32.-P. 73−87.
- Mannick J. B., Hausladen A., Liu L., Hess D. T., Zeng M., Miao Q. X., Kane L. S., Gow A. J., Stamler J. S., Fas-induced caspase denitrosylation. //Science.-1999,-Vol. 284.-P. 651−654.
- Mantzoros C.S. The role of leptin in human obesity and disease: a review of current evidence.//Ann. Intern. Med.-1999.-Vol. 130.-P. 871−881.
- Marathe S., Choi Y., Leventhal A.R., Tabas I. Sphingomyelinase converts lipoproteins from apolipoprotein E knockout mice into potent inducers of macrophage foam cell formation. //Arterioscler. Thromb. Vase. Biol.-2000.-Vol. 20.-P. 2607−2613.
- Marchesini N., Luberto C., Hannun Y.A. Biochemical properties of mammalian neutral sphingomyelinase and is rle in shingolipid mtabolism.// J. Biol. Chem.-2003.- Vol. 278, N 16.-P. 3775−13 783.
- Marczuk-Krynicka D., Hryniewiecki T., Pi^tek J., Paluszak J. The effect of brief food withdrawal on the level of free radicals and other parameters of oxidative status in the liver.//Med. Sci. Monit.-2003.-Vol. 9, N 3.-P. BR131−135.
- Markel A.J., Brook G., Aviram M. Increased plasma triglycerides, cholesterol and apolipoprotein E during prolonged fasting in normal subjects.//Postgraduate Medical Journal.-1985.-Vol. 61.-P. 395−400.
- Melino G., Bernassola F., Knight R. A., Corasaniti M. T., Nistico G., Finazzi-Agro A. S-nitrosylation regulates apoptosis. //Nature.-1997.-Vol. 388.-P. 432133.
- Mitchinson M.J., Hardwick S.J., Bennett M.R. Cell death in atherosclerotic plaques. //Curr. Opin. Lipidol.-1996.-Vol. 7.-P. 324 -329.
- Montague C.T. Congenital leptin deficiency is associated with severe early-onset obesity in humans. //Nature.-1997.-Vol. 387.-P. 903−908.
- Moron M.S., Depier J.W., Mannervik B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rar lung and liver. // Biochim. Biophys. Actaio-1979.-Vol. 582.-P. 67−78.
- Mortimore G.E., Poso A.R. Intracellular protein catabolism and its control during nutrient deprivation and supply.// Annu Rev. Nutr.-1987Vol. 7.-P. 539−64.
- Murphy P. A., Krahling J. B., Gee R., Kirk J. R., Tolbert N. E. Enzyme activities of isolated hepatic peroxisomes from genetically lean and obese male mice. //Arch. Biochem. Biophys.- 1979.-Vol. 193.-P. 179−185.
- Mutanen M. L., Mykkanen H. M. Effect of dietary fat on plasma glutathione peroxidase levels and intestinal absorption of 75Se-labeled sodium selenite in chicks. //J. Nutr.- 1984.-Vol. 114.-P. 829−834.
- Nathan C. Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling. // J. Clin. Invest.-2003.-Vol. 111, N 6.-P. 769−778.
- Neat C. E., Thomassen M. S., Osmundsen H. Induction of peroxisimal beta-oxidation in rat liver by high fat diets. //Biochem. J.-1980.-Vol. 186.-P. 369−371.
- Nicholson D.W. Caspase structure, proteolytic substrates, and function during apoptotic cell death. //Cell Death and Differentiation.-1999.-Vol. 6.-P. 1028- 1042.
- Nicotera P., Orrenius S. Role of thiols in protection against biological reactive intermediates. //Adv. Exp. Med. Biol.- 1986.-Vol. 197.-P. 41−51.
- Nilsson A., Duan R.-D. Absorbtion and lipoprotein transport of sphingomyelin.//!. Lipid Res.-2006.-Vol. 47.-P. 154−171.
- Obeid L. M., Venable M. E. Signal transduction in cellular senescence. //J. Am. Geriatr. Soc.-1997.-Vol. 45.-P. 361−366.
- Oberhammer F. A., Pavelka M., Sharma S., Tiefenbacher R., Purchio A. F., Bursch W., Schulte-Hermann R. //Proc. Natl. Acad. Sci. USA.-1992.-Vol. 89.-P. 5408−5412.
- Ohanian J., Liu G. L., Ohanian V., Heagerty A. M. Lipid second messengers derived from glycerolipids and sphingolipids, and their role in smooth muscle function.//Acta Physiol. Scand.-1998.-Vol. 164.-P. 533−548.
- Ohanian J., Ohanian V. Sphingolipids in mammalian cell signalling.//Cell. Mol. Life Sci.-2001.-Vol. 58.-P. 2053−2068.
- Ookhtens M., Hobdy K., Corvasce M.C., Aw T.Y., Kaplowitz N. Sinusoidal efflux of glutathione in the perfused rat liver. Evidence for a carrier-mediated process. //J. Clin.Invest.- 1985.-Vol. 75.-P. 258−265.
- Orellana M., Fuentes O., Rosenbluth H., Lara M., Veldts E. Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation.//FEBS.-1992.-Vol. 310, N 2.-P. 193−196.
- Orellana M., Fuentes O., Valdes E. Starvation effect on rat kidney peroxisomal and microsomal fatty acid oxidation. A comparative study between liver and kidney.//FEBS.-1993.-Vol. 322, N l.-P. 61−64.
- Otton R., Soriano F. G., Curi R. Diabetes induces apoptosis in lymphocytes.//J. Endocrinol.-2004.-Vol. 182.-P. 145−156.
- Paynter D. I. Changes in activity of the manganese superoxide dismutase enzyme in tissues of the rat with changes in dietary manganese. //J. Nutr.-1980.-Vol. 110.-P. 437−47.
- Paynter D. I., Moir R. J., Underwood E. J. Changes in activity of the Cu-Zn superoxide dismutase enzyme in tissues of the rat with changes in dietary copper. //J. Nutr.- 1979.-Vol. 109.-P. 1570−1576.
- Payraste B., Missy K., Giuriatu S., Bodin S., Plantavit M., Gratacap M.-P. Phosphoinositiodes. Key players in cell signalling, in time and space. // Cellular Signalling.-2001.-Vol. 31.-P. 377−387.
- Pelleymounter M.A., et al. Effects of the obese gene product on body weight regulation in ob/ob mice. //Science.- 1995.-Vol. 269.-P. 540−543.
- Perry D. K., Hannun Y. A. The role of ceramide in cell signaling.// Biochim. Biophys. Acta.-1998.-Vol. 1436.-P. 233−243.
- Pettus B.J., Chalfant Ch.E., Hannun Y.A. Ceramide in apoptosis: an overview and current perspectives.//Biochim. Biophys. Acta.-2002.-Vol. 1585.-P. 114- 125.
- Pires J., Curi R., Otton R. Induction of apoptosis in rat lymphocytes by starvation.// Clinical Science.-2007.-Vol. 112.-P. 59−67.
- Pollard M., Luckert P. H., Snyder D. Prevention of prostate cancer and liver tumors in L-W rats by moderate dietary restriction. //Cancer.-1989.-Vol. 64.-P. 686−690.
- Prins J., Niesler C., Winterford C., Bright N.A., Siddle K., O’Rahilly S., Walker N.I., Cameron D.P. Tumor necrosis factor-a induces apoptosis of human adipose cells. //Diabetes.-1997.-Vol. 46.-P. 1939−1944.
- Qiu H., Edmunds T., Baker-Malcolm J., Karey K. P., Estes S., Schwarz C., Hughes H., Van Patten S. M. Activation of human acid sphingomyelinase through modification or deletion of C-terminal cysteine. //J. Biol. Chem.-2003.-Vol. 278.-P. 32 744−32 752.
- Rao M.S., Reddy J.K. Peroxisomal beta-oxidation and steatohepatitis. //Semin. Liver Dis.-2001.-Vol. 21, N l.-P. 43−55.
- Reddy J. K., Lalwai N. D. Carcinogenesis by hepatic peroxisome proliferators: evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans.//Crit. Rev. Toxicol.- 1983.-Vol. 12.-P. 1−58.
- Repine J.E. Oxidant-antioxidant balance. Some observations from studies of ischemia-reperfusion in isolated perfused rat hearts. //Am. J. Med.-1991.-Vol. 91.-P. 45−53.
- Robin J.P., Frain M., Sardet C., Groscolas R., Le Maho Y. Protein and lipid utilization during long-term fasting in emperor penguins.// Am. J. Physiol. Regul. Integr. Comp. Physiol.-1998.-Vol. 254.-P. R61-R68.
- Rossig L., Fichtischerer B., Breitschopf K., Haendeler J., Zeiher A. M., Mulsch A., Dimmeier S. Nitric oxide inhibits caspase-3 by S-nitrosation in vivo. //J. Biol. Chem.-1999.-Vol. 274.-P. 6823−6826.
- Roy S., Nicholson D.W. Cross-talk in cell death signaling. //J. Exp. Med.-2000.-Vol. 192.-P. 21 29.
- Ruvolo P.P. Intracellular signal transduction pathways activated by ceramide and its metabolites.//Pharmacological Research.-2003.-Vol. 47.-P. 383 392.
- Ruvolo P.P. Ceramide regulates cellular homeostasis via diverse stress signaling pathways.// Leukemia.-2001.^-Vol. 15.-P. 1153−1160
- Ruvolo P.P., Deng X., Ito T., Carr B.K., May W.S. Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A.//J Biol Chem.-1999.-Vol. 274:20 296−300.
- Salymoss B.C., Bourassa M.G., Varga S. et al. Incidence and clinical characteristics of the metabolic syndrome in patients with coronary artery disease. Coron Artery Dis.-2003.-Vol. 3.-P. 207−212.
- Samad F. Contribution of sphingolipids to the pathogenesis of obesity .//Future Lipidol.-2008.-Vol. 2.-P. 625−639.
- Samad F., Hester K. D., Yang G., Hannun Y.A., Bielawski J. Altered adipose and plasma sphingolipid metabolism in obesity. A potential mechanism for cardiovascular and metabolic risk. // Diabetes.-2006, Vol. 55.-P. 2570−2587.
- Samali A., Nordgren H., Zhivotovsky B., Peterson E., Orrenius S. A comparative study of apoptosis and necrosis in HepG2 cells: oxidant-induced caspase inactivation leads to necrosis. //Biochem. Biophys. Res. Commun.-1999.-Vol. 255.-P. 6−11.
- Samra J.S. Sir David Cuthbertson Medal Lecture. Regulation of lipid metabolism in adipose tissue. //Proc. Nutr. Soc.-2000.-Vol. 59, N 3.-P. 441−446.
- Sawai H., Hannun Y.A.- Ceramide and sphingomyelinases in the regulation of stress responses.//Chemistry and Physics of Lipids.-1999.-Vol. 102.-P. 141−147.
- Schoonjans K., Staels B., Auwerx J. Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression.// J. Lipid Res.-1996.-Vol. 7.-P. 907−925.
- Schuchman, E.H., Suchi, M., Takahashi, T., Sandhoff, K., Desnick, R.J. Human acid sphingomyelinase. Isolation, nucleotide sequence and expression of the full-length and alternatively spliced cDNAs.// J. Biol. Chem.-1991.-Vol. 266.-P. 8531−8539.
- Sewter C.P., Digby J.E., Blows F., Prins J., O’Rahilly S. Regulation of tumor necrosis faktor-alpha release from human adipose tissue in vitro. //J. Endocrinology.- 1999.-Vol. 163.-P. 33−38.
- Shah C., Yang G., Lee I., Bielawski J., Hannun Y.A., Samad F. Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1. //J. Biol. Chem.-2008.-Vol. 283.-P. 13 538−13 548.
- Shimazu T., Tokutake S., Usami M. Inactivation of phosphorylase phosphatase by a factor from rabbit liver and its chemical characterization as glutathione disulfide.// J. Biol. Chem.- 1978.-Vol. 253.-P. 7376−7382.
- Shimizu M., Morita S. Effects of feeding and fasting on hepatolobular distribution of glutathione and cadmium-induced hepatotoxicity. //Toxicology.-1992.-Vol. 75.-P. 97−107.
- Slee E.A., Adrain C., Martin S.J. Serial killers: Ordering caspase activation events in apoptosis. // Cell. Death. Differ.-1999.-Vol. 6.-P. 1067−1077.
- Speakman J. R., Hambly C.-Starving for Life: What Animal Studies Can and Cannot Tell Us about the Use of Caloric Restriction to Prolong Human Lifespan.//!. Nutr.-2007.-Vol. 137.-P. 1078−1086.
- Spiegel S., Foster D., Kolesnick R. Signal transduction through lipid second messengers.//Current Opinion in Cell Biology.-1996.-Vol. 8.-P. 159−1 67.
- Spiegel S., Merrill A.H. Sphingolipid metabolism and cell growth regulation.//FASEB J.-1996.-Vol. 10.-P. 1388−97.
- Stennicke H.R., Salvesen G.S. Biochemical characteristics of caspases-3, -6, -7, and -8. //J. Biol. Chem.-1997.-Vol. 272, N. 41.-P. 25 719−25 723.
- Stratakis C.A., Chrousos G.P. Neuroendocrinology and pathophysiology of the stress system. // Stress. Basic mechanisms and clinical implications.-New York: New York Academy of Sciences, 1995.-P.1−18.
- Strubelt O., Dost-Kempf E., Siegers C.-P., Younes M., Volpel M., Preuss U., Dreckmann J.G. The influence of fasting on the susceptibility of mice to hepatotoxic injury. //Toxicol. Appl. Pharmacol.- 1981.-Vol. 60.-P. 66−77.
- Summers S.A., Nelson D.H. A role for sphingolipids in producing the common features of type 2 diabetes, metabolic syndrome X, and Cushing’s syndrome. //Diabetes.-2005.-Vol. 54.-P. 591−602.
- Taggart A.K., Kero J., Gan X., Cai T.Q., Cheng K., Ippolito M., et al. (D)-beta—hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G. //J. Biol. Chem.-2005.-Vol. 280.-P. 26 649 -26 652.
- Taha T.A., Mullen T.D., Obeid L.M. A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death.//Biochim. Biophys. Acta.-2006.-Vol. 1758.-P. 2027−2036.
- Takeda Y., Tashima M., Takahashi A. Uchiyama T., Okazaki T. Ceramide generation in nitric oxide-induced apoptosis. Activation of magnesium-dependent neutral sphingomyelinase via caspase-3.//J. Biol.Chem.-1999.-Vol. 274.-P. 10 654−10 660.
- Tate D.J., Miceli M.V., Newsome D.A. Zinc induces catalase gene expression in cultured fetal human retinal pigment epithelial cells.// Curr. Eye Res.-1997.-Vol. 16.-P. 1017−1023.
- Tateishi N., Higashi T., Naruse A., Narashima K., Shiozaki H., Sakamoto Y. Rat liver glutathione: possible role as a reservoir of cysteine. //J. Nutr.-1977.-Vol. 107.-P. 51−60.
- Tessitore L. Apoptosis and cell proliferation are involved in the initiation of liver carcinogenesis by a subnecrogenic dose of diethylnitrosamine in refed rats. //J. Nutr.- 2000,-Vol. 130.-P. 104−110.
- Thissen J.P., Underwood L. F, Ketelslegers J.M. Regulation of insulinlike growth factor-I in starvation and injury.//Nutr. Rev.-1999.-Vol. 57.-P. 167−176.
- Thompson J.R., Wu G. The effect of ketone bodies on nitrogen metabolism in skeletal muscle. //Comp. Biochem. Physiol. B.-1991.-Vol. 100.-P. 209−216.
- Tomasi C., Laconil E., Laconil S., Greco M., Sarma D.S.R., Pani P. Effect fasting/refeeding on the incedence chemically induced hepatocellular carcinoma in the rat. // Carcinogenesis.-1999.-Vol. 20, N 10.-P. 1979−1983.
- Tomiuk S., Hofmann K., Nix M., Zumbansen M., Stoffel W. Cloned mammalian neutral sphingomyelinase: Functions in sphingolipid signaling? // Proc. Natl. Acad. Sci. USA.- 1998.-Vol. 95.-P. 3638−3643.
- Trayhurn P., Thomas M.E.A., Duncan J.S., Rayner D.V. Effects of fasting and refeeding on Ob gene expression in white adipose tissue of lean and obese mice.// FEBS Lett.-1995.-Vol. 368.-P. 488190.
- Urbano A., Lakshmanan U., Choo P.H., et al. AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells. // EMBO.- 2005.-Vol. 24.-P. 2815−2822.
- Vaisman N., Schattner A., Hahn T. Tumor necrosis factor production during starvation. //Am. J. Med.-1989.-Vol. 87.-P. 115- 126.
- Van den Berghe G. The role of the liver in metabolic homeostasis: implications for inborn errors of metabolism. //J. Inherit. Metab. Dis.- 1991.-Vol. 14.-P. 407−420.
- Van Den Branden C., Kerckaert I., Roels F. Peroxisomal (3-oxidation from endogenous substrates. Demonstration through H202 production in the unanaesthetized mouse. //Biochem. J.-1984.-Vol. 218.-P. 697−702.
- Varady K.A., Hellerstein M.K. Alternate-day fasting and chronic disease prevention: a review of human and animal trials.// Am. J. Clinical Nutrition.-2007.-Vol. 86.-P. 7−13.
- Verheij M., Bose R., Lin X.H., Yao B., Jarvis W.D., Grant S., et al. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. //Nature.- 1996.-Vol.-P. 380.75−79.
- Vernon R.G., Denis R.G., Sorensen A. Signals of adiposity. //Domest. Anim. Endocrinol.-2001.-Vol. 21, N 4.-P. 197−214.
- Vina J., Borras C., Gambini J., Sastre J., Pallardo F. V.-Why Females Live Longer Than Males: Control of Longevity by Sex Hormones.//Sci. Aging Knowl. Environ.-2005.-P. 17.
- Walczak H., Krammer P.H. The CD95 (APO-l/Fas) and the TRAIL (APO-2L) apoptosis systems. //Exp. Cell. Res.-2000.-Vol. 256.-P. 58- 69.
- Wanders R.J.A. Peroxisomes, lipid metabolism, and peroxisomal disorders. //Molecular Genetics and Metabolism.-2004.-Vol. 83.-P. 16−27.
- Wang, X. Lipid signaling. // Current Opinion in Plant Biology 2004.- № 7.-P. 329−336.
- Weigle, D.S., et al. Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels. //J. Clin. Endocrinol. Metab.-1997.-Vol. 82.-P. 561−565.
- Wellbourne T.C., Milford L., Carter P. The role of growth hormone in substrate utilization.// Baillieres Clin. Endocrinol. Metab.-1997.-Vol. 1 l.-P. 699 -707.
- Wohaieb S. A., Godin D. V. Starvation-related changes in free radical tissue defense mechanisms in the rat. //Diabetes.- 1987.-Vol. 36.-P. 169−173.
- Won Je-Seong, Singh Inderjit. Sphingolipid signaling and redox regulation.//Free Radic. Biol. Med.-2006.-Vol. 40.-P. 1875−1888.
- Xia Y., Hill K. E, Burk R.E. Effect of selenium deficiency on hydroperoxide-induced glutathione release from the isolated perfused rat heart. //J. Nutr.- 1985.-Vol. 115.-P. 733−742.
- Yan F., Polk D.B. Kinase suppressor of ras is necessary for tumor necrosis factor alpha activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in intestinal epithelial cells. //Cancer Res.-2001.-Vol. 61.-P. 963 969.
- Yang G., Badeanlou L., Bielawski J., Roberts A.J., Hannun Y.A., Samad F. Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome.// Am. J. Physiol. Endocrinol. Metab.-2009.-Vol. 297.-P. E211-E224.
- Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human homologue.// Nature.-1994.-Vol. 372.-P. 425−432.
- Zhang Z., Miyatake S., Saiki M. et al. Selenium and glutathione peroxidase mRNA in rat glioma. //Biol. Trace Elem. Res.-2000.-Vol. 71.-P. 67−76.
- Zimmerman K.C., Bonzon C., Green D.R. The machinery of programmed cell death. //Pharmacol. Ther.-2002.-Vol. 92.-P. 57- 70.