Репликативное метилирование ДНК в L — клетках мыши
Диссертация
Установлено, что репликативное метилирование ДНК в Lклетках осуществляется в два этапа в соответствии с двумя этапами синтеза ДНК: а) на первом этапе метилируются фрагменты Оказаки сразу в ходе синтеза и окончательно так, что в них модифицируется примерно половина всех CpG — сайтовб) на втором этапе метилируются только линкерные участки ДНК, в которых метилируются все CpG — сайты. В целом… Читать ещё >
Список литературы
- Башките Е.А. Влияние фитогормонов на метилирование ДНК у высших растений. Дис.. канд.биол.наук, Вильнюс, 1979.
- Башките Е.А., Кирнос М. Д., Кирьянов Г. И., Александрушкина Н.И.,
- Ванюшин Б.Ф. Репликация и метилирование ДНК в клетках суспензионной культуры табака и влияние ауксина. Биохимия, 1980, т.45, с.1448−1456.
- Босток К., Самнер Э. В кн.: Хромосома эукариотической клетки.1. М., Мир, 1981, C.254−25S.
- Бурцева Н.Н., Демидкина Н. П., Азизов Ю. М., Ванюшин Б. Ф. Изменение специфичности метилирования ДНК в лимфоцитах крови крупного рогатого скота при хроническом лимфолейкозе. Биохимия, 1978, т.43, с.2082−2091.
- Ванюшин Б.Ф. Определение нуклеотидного состава нуклеиновыхкислот. В кн.: Современные методы в биохимии. М., Медицина, 1964, T. I, с.235−248.
- Ванюшин Б.Ф. Метилирование ДНК и его биологическое значение.
- Успехи совр. биологии, 1968, т.65, с.163−185.
- Ванюшин Б.Ф. Метилирование ДНК в клетках различных организмов.
- Успехи совр. биологии, 1974, т.77, с.68−90.
- Ванюшин Б.Ф., Тушмалова Н. А., Гуськова Л. В., Демидкина Н.П.,
- Никандрова Л.Р. Изменение уровня метилирования ДНК в коре головного мозга крыс при выработке условных рефлексов. Мол. биол., 1977, т. II, с.181−187.
- Ванюшин Б.Ф., Романенко Е. Б. Изменение метилирования ДНК крысв онтогенезе и под воздействием гидрокортизона. Биохимия, 1979, т.44, с.78−85.
- Ванюшин Б.Ф. Метилщювание ДНК у эукариот новый механизм ре- 139 гуляции экспрессии генов и клеточной дифференцировки. Успехи биол. химии, 1983, т.24, с.170−193.
- Георгиев Г. П., Бакаев В. В. Три уровня структурной организациихромосом эукариот. Мол.биол., 1978, т.12, № б, с.1205−1270.
- Девидсон Дж. В кн.: Биохимия нуклеиновых кислот. М., Мир, 1976, с. 140,163.
- Демидкина Н.П., Кирьянов Г. И., Ванюшин Б. Ф. Метилированиевновь синтезированной ДЖ в культуре мышиных фиброблас-тов. Биохимия, 1979, т.44, J® 8, с.1416−1426.
- Демидкина Н.П. Метилирование ДНК в клетках животных и связьего с репликацией. Дис.. канд.биол.наук, М., 1979.
- Добрица А.П., Михайлов А. А., Ванюшин Б. Ф. Метилирование ДНКфага 1Р? ф Bac.brevis var G.-B. Биохимия, 1975, т.40, с.1269−1274.
- Дрожденюк А.П., Сулимова Г. Е., Ванюшин Б. Ф. Содержание 5-метилцитозина в разных классах повторяющихся последовательностей ДНК некоторых высших растений. Биохимия, 1977, т.42, с.1439−1444.
- Караванов А.А. Транскрипционно-активные участки хроматина.
- Онтогенез, 1983, т.14, № 4, с.339−359.
- Карпенчук К.Г., Минченкова А. Е., Венгеров Ю. Ю., Ундрицов Н.М.,
- Мирзабеков А.Д. Разворачивание коровых нуклеосом, вызванное химическим ацетилированием гистонов. Мол.биол., 1983, т.17, с.855−867.
- Кирнос М.Д., Александрушкина Н. И., Ванюшин Б. Ф. 5-метицитозин в пиримидиновых последовательностях ДНК растений и животных: специфичность метилирования. Биохимия, 1981, т.46, с.1458−1474.
- Кирнос М.Д., Ганичева Н. И., Кутуева Л. И., Ванюшин Б.Ф.
- Нерепликативные синтез и метилирование ДНК в клеточном цикле клеток первого листа этиолированных проростов пшеницы. Биохимия, 1984, т.49, с.1690−1702.
- Кирьянов Г. И., Романов Г. А., Ванюшин Б. Ф. Внутригеномное распределение 5-метилцитозина в ДНК некоторых эукариот. Докл. АН СССР, 1974, т.219, с.1007−1009.
- Кирьянов Г. И., Исаева Л. В., Кирнос М. Д., Ганичева Н. И., Ванюшин Б. Ф. Реплжативное метилирование ДНК в l -клетках: действие s -изобутиладенозина и циклогексимида и возможное существование двух ДНК-метилаз. Биохимия, 1982, т.47, с.153−161.
- Корнберг А. В кн.: Синтез ДНК. М., Мир, 1977, с.164−218. 24. Нестеренко В.Ф., Бурьянов Я. И., Баев А. А. Выделение и свойства ДНК-цитозин-метилазы I из Escherichia coli МЕЕ — 600.
- Биохимия, 1979, т.44, № I, с.130−141.
- Перепеленко С.Д., Бурьянов Я. И., Баев А. А. Особенности метилирования бактериальными ДНК-метилазами эукариотных ДНК, содержащих различное количество 5-метилцитозина. Докл. АН СССР, 1980, т.250, 6, с.1480−1483.
- Романенко Е.Б., Обухова Л. К., Ванюшин Б. Ф. Изменение метилирования ДНК у мышей с возрастом, под влиянием гидрокортизона и антиоксиданта. Биол. науки, 1981, № 2, с.63−70.
- Романов Г. А., Кирьянов Г. И., Дворкин В. М., Ванюшин Б.Ф.
- Влияние гидрокортизона на метилирование и молекулярную популяцию ДНК в печени крыс. Биохимия, 1976, т.41, с.1038−1043.
- Романов Г. А., Ванюшин Б. Ф. Метилирование ДНК у эукариот. I.
- Метилируемые последовательности и ДНК-метилазы. Биол. науки, 1980, № II, с.5−20.
- Смирнов В.Г., Романов Г. А., Ванюшин Б.ф. Содержание 5-метилцитозина в разной степени повторенности последовательностях ДНК печени крыс и его изменения при индукции гидрокортизоном. Докл. АН СССР, 1977, т.232, с.961−933.
- Смирнова Т.А. Нуклеомерный уровень организации хроматина:структура и сравнительная характеристика доступности ДНК для узнавания ДНК-метилазами. Дис.. канд.биол.наук, Киев, 1983.
- Спирин А.С. Спектрофотометрическое определение суммарногоколичества нуклеиновых кислот. Биохимия, 1958, т.23, № 5, с.356−658.
- Сулимова Г. Е., Мазин А. Л., Ванюшин Б. Ф., Белозерский А.Н.
- Содержание 5-метилцитозина в различных по составу фракциях ДНК высших растений. Докл. АН СССР, 1970, т.193, с.1422−1425.
- Сулимова Г. А., Дрожденюк А. П., Ванюшин Б. Ф. Изменение метилируемых последовательностей и молекулярной популяции ДНК пшеницы при прорастании. Мол.биол., 1978, т.12, с.496−504.
- Федоров Н.А., Корешкова Н. А. Метилирование вновь синтезированной ДНК в культуре клеток костного мозга крыс. Докл. АН СССР, 1973, т.209, с.231−233.
- Федоров Н. А, Овчарук И. Н., Борисов Б. Н., Ванюшин Б. Ф. Метилирование вновь синтезированной ядерной ДНК регенерирующей печени крыс. Докл. АН СССР, 1977, т.236, с.1256−1259.
- Федоров Н.А., Паньков В. Н. Содержание 5-метилцитозина во фракциях ДНК лейкоцитов человека в норме и при хронических лейкозах. Вопр.мед.химии, 1983, т.29, с.89−92.
- Adams R.L.P. Incorporation of 5- %.-uridine into DNA.- FEBS1.t., 1968, v.2, p.91.
- Adams R.L.P. The relationship between synthesis and methylation of DNA in mouse fibroblasts.- Biochem.Biophys.Acta, 1971, v.254, p.205−212.
- Adams R.L.P., Hogarth C. DNA methylation in Isolated nuclei: old and new DNA-s are methylated. Biochem.Biophys.Acta, 1973, v.331, p.214−220.
- Adams R.L.P. New synthesized DNA is not methylation.- Biochem. Biophys. Acta, 1974, v.335, p.365−373.
- Adams R.L.P., Mc Kay E.L., Douglas J.Т., Burdon R.H. Methylation of nucleosomal and nuclease sensitive DNA.- Nucl. Acids Res., 1977, v.4, p.3097−4009.
- Adams R.L.P., Mc Kay E.L., Craig L.M., Burdon R.H. Methylation of mosquito DNA.- Biochem.Biophys.Acta, 1979, v.563, p.72−81.
- Adams R.L.P., Burdon R.H. DNA methylation in eucaryotes.
- Crit.Rev.Biochem., 1982, v.13, N 4, p.349−384.
- Agutter P. S. The isolation of the envelopes of rat livernuclei.- Biochem.Biophys.Acta, 1972, v.255, p.397−401.
- Alberts B., Steraglanz R. Resent excitement in the DNA replication problem.- Nature, 1977, v.269, p.655−661.
- Alberts G., Worsel A., Weintraub H. On the biological implication of chromatin structure.- In Bradbury E.M. and Javaherian K. (ed). The organization and expression of the eucaryotic genome. Academic Press Inc., 1977, New York, p.165−191.
- Albright S.C., Wiseman J.M., Lange R.A., Garrard W.T. Subunit structures of different electrophoretic forms of nucleosomes.- J.Biol.Chem., 1980, v.255, p.3673−3684.
- Allan G.J., Hartman P.G., Crane-Robinson C., Avilis F.G.J.
- The structure of histone H1 and its location in chromatin.- Nature, 1980, v.288, p.675−679.
- Anderson S., Kaufman G., De Pamphilis M.L. RNA primers in
- SV 40 DNA replication- identification of transient HNA -DNA covalent linkages in replicating DNA.- Biochemistry, 1977, v.16, N 23, p.4990−4998.
- Anderson S., De Pamphilis M.L. Metabolism of Okazaki fragments during SV 40 DNA replication.- J.Biol.Chem., 1979, v.254, p.11 495−11 504.
- Annunziato А.Т., Schindler R.K., Thomas C.A., Seale R.L.
- Dual nature of newly replicated chromatin.- J.Biol.Chem., 1981, v.256, p.11 880−11 886.
- Annunziato А.Т., Seale R.L. Maturation of nucleosomal andnonnucleosomal components of nascent chromatin: differential requirements for concurrent protein synthesis.- Biochemistry, 1982, v.21, p.5431−5438.
- Annunziato А.Т., Seale R.L. Histone deacetylation is required for the maturation of newly replicated chromatin.- J. Biol.Chem., 1983, v.258, N 20, p.12 675−12 684.
- Belyavsky A.V., Bavykin S.G., Goguadze E.G., Mirzabekov A.D.
- Primary organization of nucleosomes containing all five histones and DNA 175 and 165 baze pair long.- J.Mol. Biol., 1980, v.139, p.519−536.- 144
- Bernemaxi A., Robert Gero M., Vigier P. DNA raethylase activity associated with rous sarcoma virus.- FEBS Let., 1978, v.89, N 1, p.33−36.
- Billen D. Methylation of the bacterial chromosome: an eventat the «replication point»? J.Mol.Biol., 1968, v.31, N 3, p.477−486.
- Bird A.P. Use of restriction enzymes to study eucaryotic DNAmethylation. The symmetry of methylated sites supports semiconservative copying of the methylation pattern.- J. Mol.Biol., 1978, v.118, p.49−60.
- Bird A.P. DNA methylation and the frequency of CpG in animal
- DNA.- Nucl. Acids Res., 1980, v.8, p.1499−1504.
- Bloch S., Cedar H. Methylation of chromatin DNA.- Nucl. Acids
- Res., 1976, v.3, p.1507−1519.
- Blumenthal А.В., Clark E.J. Replication subunits in the synthesis of Drosophila DNA.- Exp. Cell Res., 1977, v.105, p.15−26.
- Browne M.J., Burdon R.H. The sequence specificity of vertebrate DNA methylation.- Nucl. Acids Res., 1977, v.4, p. 1025-Ю37.
- Browne M.J., Cato A.C.B., Burdon R.H. The distribution ofmodified and nonmodified C-G doublets in BHK-21 cell DNA.-FEBS Let., 1978, v.91, p.69−73.
- Brun G., Weissbach A. Initiation of HeLa cell DNA synthesisin a subnuclear system.- Proc. Nat .Acad. Sci USA, 1978, v.75, p.5931−5935.
- Bryant J.A. Biochemical aspects of DNA replication with particular reference to plants.- Biol.Rev., 1980, v.55, p. 237−284.
- Bugler В., Bertaux 0., Valencia R. Nucleic acids methylationof synchronized ВНЕ 21 HS 5 fibroblasts during the mitotic phase.- J. Cell Physiol., 1980, v.103, p.149−157.
- Burden R.H., Adams R.b.P. The in vivo methylation of DNA inmouse fibroblasts.- Biochem.Biophys.Acta, 1969″ v.174″ p.322−329*
- Burdon R.H., Douglass J.T. The influence of subcellular fractions on the enzyme methylation of DNA in ascites cell nuclei.- Nucl. Acids Res., 1974, v.1, p.97−103.
- Byrner J.J., Black V.L. Comparison of DNA polymerases cL and
- S from bone marrow.- Biochemistry, 1978, v.17″ p.4226−4231.
- Camerini-Otero R.D., Felsenfeld G. Supercoiling energy andnucleosome formation the role of arginine-rich kernel.-Nucl. Acids Res., 1977, v.4, p.1159−1181.
- Cartwright I.L., Abmayr S.M., Fleischmann G., Lowenhaupt K.,
- Elgin S.C.R., Keene M.A. Chromatin structure and gene activity: the role of nonhistone chromosomal proteins.-Crit.Rew.Biochem., 1982, v.13, p.1−86.
- Cedar H., Solage A., Glaeer G., Rasin A. Direct detection ofmethylated cytosine in DNA by use of the restriction enzyme Msp I.- Nucl. Acids Res., 1979, v.6, p.2125−2135.
- Chao M.V., Gralla J.D., Martinson H.G. lac -Operator nucleosomes. 1. Repressor binds specifically to operator within the nucleosome core.- Biochemistry, 1980a, v.19, p.3254--3260.
- Chao M.V., Martinson H.G., Gralla J.D. lac Operator nucleosomes. 2.1ac nucleosomes can change conformation to strengthen binding by lac-repressor.- Biochemistry, 1980b, v.19, p.3260−3269.
- Chestier A., Yaniv M. Rapid turnover of aoetil groups in thefour core histones of simian, virus 40 minichromosomes.-Proc.Nat.Acad.Sci USA, 1979, v.76, p.46−50^
- Coulondre 0., Miller J.H., Farabaugh P.J., Gilbert W. Molecular basis of base substitution hotspots in Escherichia coli.- Nature, 1978, v.274, p.775−780.
- Covault J., Chalkley R. The identification of distinct population of acetylated histone.- J.Biol.Chem., 1980, v.255, p.9110−9116.
- Cox R., Prescott C., Yrving C. The effect of S-adenosylhomocystein on DNA methylation in isolated rat liver nuclei.-Biochem.Biophys.Acta, 1977, v.474, p.493−499.
- Cremisi C., Chestier A., Yaniv M. Assembly of SV 40 and polyoma mini. chromosomes during replication.- Cold Spring Harbor Symp.Quant.Biol., 1978, v.42, p.409−416.
- Cremisi C., Chestier A., Yaniv M. Preferential associationof newly synthesized histones with replicating DNA.- Cell, 1978, v.12, p.947−951.
- Cremisi C. Chromatin replication revealed by studies of animal cells and papovaviruses (simian virus 40 and polyoma virus).- Microbiol.rev., 1979, v.43, p.297−310.
- Cusick М.Б., Herman Т.Н., De Paraphilia M.L., Wasserman P.M.
- Structure of chromatin at deoxyribonucleic acid replication forks: prenucleosomal deoxyribonucleic acid is rapidly excised from replicating simian virus 40 chromosomes by micrococcal nuclease.- Biochemistry, 1981, v.20, p.6648--6658.
- Cusick M.S., Lee K.-S., De Pamphilis M.L., Wasserman P.M.
- Structure of chromatin at deoxyribonucleic acids forks: nuclease hypersensitivity results from both prenucleoso- 147 mal deoxyribonucleic acids and immature chromatin structure.- Biochemistry, 1983, v.22, p.3873−3884.
- D,*Anna J.A., Prentis D. A, Chromatin structural changes insynchronized cells blocked in early S-phase sequential use of isoleucine deprivation and hydroxyurea blockade.-Biochemistry, 1983, v.22, p.5631−5640.
- De Pamphilis M.L., Wasserman P.M. Replication of eucaryoticchromosomes- a close-up of the replication fork.- Ann.Rev. Biochem., 1980, v.49, p.627−666.
- Doenecke D. Modification of DNA in chromatin with methyltransferase from Haemophilus influenzae Rd.- Eur.J.Biochem., 1979, v.93, p.481−486″
- Drahovsky D., Lacko I., Wacker A. Enzymatic DNA methylationduring repair synthesis in nonproliferating human peripheral lymphocytes.- Biochem.Biophys.Acta, 1976, v.447, p.139−143.
- Edenberg H.J., Huberman J.A. Eucaryotic chromosome replication.-Ann.Rev.Genet., 1975, v.9, p.245−284.
- Eichler D.C., Wang T.S.P., Glyton D.A., Korn D. In vitro, replication of mitochondrial DNA.- J.Biol.Chem., 1977, v, 292, p.7888−7893.
- Ehrlich M., Wang R.Y.H. 5-Methylcytosine in eucaryotic DNA.
- Science, 1981, v.219, p.1350−1357.- 148
- Elgin S.C.R., Weintraub H. Chromosomal proteins and chromatin structure.-Ann. Rev. Biochem., 1975, v.44, p.725−764.
- Eliasson R., Reichard P. Replication of polyoma DNA. in isolated nuclei. VII. Initiator RNA synthesis during nucleotide depletion.- J.Mol.Biol. 1979, v.129, p.393−409.
- Felsenfeld G. Chromatin.- Nature, 1978, v.271, p.115−122.
- Felsenfeld G., Nickol J., Behe M., Mc Ghee J., Jackson D.
- Methylation and chromatin structure.- Cold Spring Harbor Symp.Quant.Biol., 1983, v.47, p.577−584.
- Pinch J.Т., Klug A. Solenoidal model for superstructure inchromatin.- Proc.Nat.Acad.Sci USA, 1976, v.73, p.1897−1901.
- Pinch J.Т., butter L.C., Rhodes D., Brown R.S., Rushton В., 1. vitt M., Klug A. Structure of nucleosome core particless of chromatin.- Nature, 1977, v.269, p.29−36.
- Fisher P.A., Wang T.S.-F., Korn D. Enzymological characterisation of DNA polymerase сб.- J.Biol.Chem., 1979, v.254, p.6128−6137.
- Francke В., Vogt M. In vitro polyoma DNA synthesis: selfannealing properties of short DNA chains.- Cell, 1975, v.5, p.205−211.
- Freedlender E.F., Taichmann L., Smithies 0. Nonrandom distribution of chromosomal proteins during cell replication.-Biochemistry, 1977, v.16, p.1802−1808.
- Galili G., Levy A., Jakob K.M. Changes in chromatin structureat the replication fork. The DNPs containing nascent DNA and a transient chromatin modification detection by DNA ase I.- Nucl. Acids Res., 1981, v.9, p.3991−4005.
- Galili G., Levy A., Jakob K.M. Changes in chromatin structure at the replication fork.- J.Biol.Chem., 1983, v.258, p.11 274−11 279.
- Garel A., Zolan М., Axel R. Genes transcribed at diverserates have similar conformation in chromatin.-Pro с.Nat. Acad. Sci USA, 1977, v.74, p.4867−4671.
- Gold M., Hurwitz J. Theenzymatic methylation of ribonucleicacid and DNA.- J.Biol.Chem., 1964, v.239, p.3866−3871.
- Gomez-Eichelman M.C., Lark K.G. Endo R Dpn I restriction of
- Escherichia coli DNA synthesized in vitro. Evidence that the ends of Okazaki pieces are determined by template deoxynucleotide sequence.- J.Mol.Biol., 1977″ v.117, p.621−635.
- Gruenbaum Y., Szyf M., Cedar H., Razin A. Methylation ofreplicated and post-replicated mouse L-cell DNA.- Proc. Nat.Acad.Sci USA- 1983, v.80, p.4919−4921.
- Guseinov V.A., Kiryanov G.I., Vanyushin B.F. Intragenomedistribution of 5-methylcytosine in DNA of healthy and wiltinfected cotton plants.- Mol.Biol.Reports, 1975, v.2, p.59−63.
- Hancock R. Assembly of new nucleosomal histones and new DNAinto chromatin.- Proc.Nat.Acad.Sci USA, 1978, v.75, p.2130−2134.
- Hand R. Regulation of DNA replication on subchromosomalunits of mammalian calls.-J.Cell Biol., 1975, v.64,p.89−97.- 150
- Hand. R. Eucaryotic DNA: organization of the genome for replication.- Cell, 1978, v.15″ p.317−325.
- Hildebrand C.E., Walters R.A. Rapid assembly on newly synthesized DNA into chromatin subunits prior to joining of small DNA replication intermediates.- Biochem.Biophys.Res. Commun., 1976, v.73, p.157−163.
- Horz W., Igo-Kemenes Т., Pfeiffer W., Zachau H.G. Specificcleavage of chromatin by restriction nucleases.- Nucl. Acids Res., 1976, v.3, p.3213−3226.
- Hozier J., Renz M., Nehls P. The chromosoma fiber: evidencefor an ordered superstructure of nucleosomes.- Chromosoma, 1977″ v.62, p.301−317*
- Huberman J.A., Riggs A.D. On the mechanism of DNA replication in mammalian chromosomes.- J.Mol.Biol., 1968, v.32, p.327−341.
- Hunter Т., Francke В., Bachler L. In vitro polyoma DNA synthesis: asymmetry of short ША chain.- Cell, 1977″ v.12, p.1021−1028.
- Jackson V., Granner D., Chalkley R. Deposition of histoneonto the replicating chromosome: newly synthesized histone is not found near the replication fork.- Proc.Nat. Acad. Sci USA, 1976, v.73, p.2266−2269.
- Jackson V., Chalkley R. A new method for the isolation ofreplicative chromatin: selective deposition of histone on both new and old DNA.- Cell, 1981, v.23, p.121−134.
- Jackson V., Chalkley R. A reevaluation of new histone deposition on replicating chromatin.- J.Biol.Chem., 1981, v.256, N 10, p.5095−5103.
- Jackson V., Marshall S., Chalkley R. The sites of depositionof newly synthesized histone.- Nucl. Acids Res., 1981, v.9, N 18, p.4563−4581.
- Johnson E.M., Allfrey V.G., Bradbury E.M., Matthews H.R.
- Altered nucleosome structure containing DNA sequences complementary to 19S and 26S ribosomal RNA in Physarum poly-cephalum.- Proc. Nat .Acad. Sci USA, 1978, v.75, p. 1116−1120.
- Jones P.A., Taylor S.M. Cellular differentiation, cytidineanalogous and DNA methylation.- Cell, 1980, v.20, p.85−93.
- Kappler J.W. The kinetics of DNA methylation in cultures ofa mouse adrenal cell line.- J. Cell Physiol., 1970, v.75, p.21−32.
- Kiryanov G.I., Manarashjan T.A., Polyakov V.Yu., Pais D.,
- Chentsov Yu.S. Levels of granular organisation of chromatin fibers.- FEBS Let., 1976, v.67, p.323−327.г- 15 2
- Kiryanov G.I., Kimos M.D., Demidkina N.P., Alexandrushkina N.I., Vanyushin B.F. Methylation of DNA in L-cell on replication.- PEBS Let., 1980, v.112, p.225−228.
- KLempnauer K.H., Panning E., Otto B., Knippers R. Maturation of newly replicated chromatin of simian virus 40 and its host cell.- J.Mol.Biol., 1980, v.136, p.359−374.
- Kornberg R.D. Chromatin structure a repeating unit histonesand DNA.- Science, 1974, v.184, p.868−871.
- Kornberg R.D. Structure of chromatin.- Ann.Rev.Biochem., 1977, v.46, p.931−954.
- Kornberg A. The enzymatic replication of DNA.- Crit.Rev.
- Biochem., 1979, v.7, p.23−43.
- Kowalski J., Denhardt D. Ribonucleotides in DNA newly synthesized in 3T6 cells in vivo.- Nature, 1979, v.281, p.704--706.
- Krokan H., Cooke L., Prydz H. DNA synthesis in isolated Hebacell nuclei. Evidence for in vitro of synthesis of small pieces of DNA and their subsequent ligation.- Biochemistry, 1975, v.14, p.4233−4237.
- Kurosawa Y., Okazaki R. Mechanism of DNA chain growth. XIII.
- Evidence for discontinuous replication of both strands of P2 phage DNA.- J.Mol.Biol., 1975, v.24, p.229−241.
- Lapeyre J.-N., Maizel A.L., Becker P.P. DNA methylation ofliver and HTC cells during corticosteroid induction.-Biochem. Biophys. Res. Commun., 1980, v.95, p.630−637.
- Lark C. Studies on the in vivo methylation of DNA in Escherichia coli 15T".- J.Mol.Biol., 1968a, v.31, N 3, p.389−399.- 15:3
- Laskey R.A., Honda B.M., Mills A.D., Pinch J.T. Nucleosomes are assembled which binds histones and transfers them to ША.- Nature, 1978, v.275, p.4−16−420.140. baskey R.A., Earnshaw W.C. Nucleosome assembly.- Nature, 1980, v.286, p.763−767.
- Leffak J.M. Stability of the conservative mode of nucleosome assembly.- Nucl. Acids Res., 1983, v.11, p.2717−2732.
- Leffak J.M. Chromatin assembly in the presence of cytosinearabinoside has a short nucleosome repeat.- Nucl. Acids Res. 1983, v.11, p.5451−5467.
- Machida Y., Okazaki Т., Okazaki R. Discontinuous replication of replicative form DNA from bacteriophage 0 X 174.-Proc.Nat.Acad.Sci USA, 1977, v.74, p.2776−2780.
- Macieira-Coelho A., Icard C., Puvion-Dutilbeub P. Defectivelinkage of DNA single strands during in vitro again of human fibroblasts.- «12 th Int.Сongr.Gerontol.», Hamburg, 1981, Abstr. vol.2″, 127.
- Mandel J.L., Chambon P. DNA methylation: organ specificvariation in the methylation pattern within and around ovalbumin and other chicken genes.-Nucl.Acids Res., 1979, v.7, p.2081−2103.
- Marinus M.G. Adenine methylation of Okazaki fragments in
- Escherichia coli.- J.Bacteriol., 1976, v.128, N 3, p.853−854.
- Martin R.F., Radford I., Pardee M. Accumulation of short
- DNA fragments in hydroxyurea treated mouse L-cells.- Biochem. Biophys. Res.Commun., 1977″ v.74, p.9−15″
- Mathews O.K., Sinha N.K. Are DNA precursors concentrated atreplication sites? Proc.Nat.Acad.Sci USA, 1982, v.79, p.302−306.
- Matsukage A., Nishizawa M., Takahashi Т., Hozumi T. In Vitrosynthesis of short DNA pieces by DNA polymerasefrom mouse myeloma.- J. Biochem., 1980, v.88, p.1869−1877.
- Mc Ghee J.D., Ginder G.D. Specific DNA methylation sites inthe visinity of the chicken ft -globin genes.- Nature, 1979, v.280, p.419−420.
- Mc Ghee J., Pelsenfeld G. Nucleosome structure.- Ann.Rev.
- Biochem., 1980, v.49, p.1115−1156.
- Meselson M., Yuan R., Heywood J. Restriction modificationenzyme system in bacteria.- Ann.Rev.Biochem., 1972, v.41,p.447−466.
- Micheli G., Baldari C.T., Carri M.T., G. diCello, Buengiorno
- Nardelli M. An electron microscopy study of chromosomal DNA replication in different eucakyotic systems.- Exp. Cell Res., 1982, v.137, p.127−140.
- Miller O.J., Schned L.W., Allen S., Erlanger B. 5-methylcytosine localized in mammalian constitutive heterochro-matin.- Nature, 1974, v.251, p.636−637.- 155
- Mirzabekov A.D., Shick V.V., Belyavsky A.V., Karpov V.L., Bavykin S.G. The structure of nucleosomes: the arrangementof histones in the DNA grooves and along the ША chain.-Cold Spring Harbor Symp.Quant. Biol., 1978, v.42, p.149--155.
- Molitor H., Drahovsky D., Wacker A. Unmethylated DNA in mouse cells. 1. ША fibre autoradiography.- Biochem.Biophys. Acta, 1976, v.432, p.28−36.
- Murphy R.F., Wallace R.B., Bonner J. Altered nucleosome spacing in newly replicated chromatin from Freind leukemia cells.- Proc.Nat.Acad.Sci USA, 1978, v.75″ p.5903−5907.
- Nagl W. Replication of the eucakyotic chromosome.- Progr.Bot., 1979, v.41, p.161−172.
- Narkhammar-Meuth M., Eliasson R., Magnusson G. Discontinuoussynthesis of both strands at the growing fork during polyoma DNA replication in vitro.- J.Virol., 1981, v.39,p.11--20.
- Narkhamraer-Meuth M., Kowalski J., Denhardt D. Both strandsof polyoma DNA are replicated discontinuously with ribonucleotide primers in vivo.- J.Virol., 1981, v.39, p.21−30.
- Noll M. Subunit structure of chromatin.- Nature, 1974, v.251,p.249−251.
- Noll M., Kornberg R.D. Action of micrococcal nuclease chromatin and the location of histone H1.- J.Mol.Biol., 1977, v.109, p.393−404.
- Okazaki R., Okazaki T", Sakabe K., Sugimoto K., Kainuma R.,
- Sugino A. In vivp mechanism of DNA chain growth.- Cold Spring Harb.Symp. Quant Biol., 1968, v.33, p.129−136.
- Okazaki R., Okazaki Т., Sakabe К., Sugimoto К., Sugino A.
- Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains.- Proc.Nat.Acad.Sci USA, 1968, v.59, p.598−605.
- Okazaki Т., Kurosawa Y., Ogawa Т., Seki Т., Shinozaki K.,
- Perlman D., Huberman G.A. A simmetric Okazaki piece synthesis during replication ofSV 40 DNA in vitro.- Cell, 1977, v.12, p.1028−1043.
- Perry M., Chalkley R. The effect of histone hyperacetylationon the nuclease sensitivity and solubility of chromatin.-J.Biol.Chem., 1981, v.256, p.3313−3318.
- Perry M., Chalkley R. Histone acetylation increases the solubility of chromatin and occurs sequentially over most of the chromatin.- J.Biol.Chem., 1982, v.257, p.7336−7347.
- Pfeiffer W., Horz W., Igo-Kemenes Т., Zachau H.G. Resrrictionnucleases as probes of chromatin structure.- Nature, 1978, v.258, p.450−452.
- Pre§ cott D.M. Reproduction, of eucaryotic cells.- Academic1. Press, New York, 1976.
- Razin A., Cedar H. Distribution of 5-methylcytosine in chromatin.- Proc.Nat.Acad.Sci USA, 1977, v.74, p.2725−2728.- 157
- Razin A., Riggs A.D. DNA methylation and gene function.
- Science, 1980, v.210, p.604−610.
- Reddy G.P.V., Singh A., Stafford M.E., Mathews O.K. Enzymeassociations in T4 phage DNA precursor synthesis.- Proc.¦. *
- Natl. Acad. Sci USA, 1977., v.74, p.3152−3156.
- Reddy G.P.V., Pardee A.B. Multienzyme complex for metabolicchanneling in mammalian DNA replication.- Proc .Natl .Acad. Sci USA, 1980, y.77, p.3312−3316.
- Reichard P., Eliasson R., Soderman G. Initiator RNA in discontinuous polyoma DNA synthesis.- Proc.Natl.Acad. Sci USA, 1974, v.71, p.4901−4905.
- Renz M., Nehls P., Hozier J. Involvement of histone H1 inthe organization of the chromosome fiber.- Proc.Nat.Acad. Sci USA, 1977, v.74, p.1879−1883.
- Riggs A.D. X inactivation, differentiation and DNA methylation.- Cytogenet. Cell Genet., 1975, v.14, p.9−25.
- Riley D., Weintraub H. Conservative segregation of parentalhistones during replication in the presence of cyclohexi-mide.- Proc.Natl.Acad. Sci USA, 1979, v.76, p.328−332.
- Robert-Gero A., Lawrence P., Farrugia G., Berneman A.,
- Blanchard P., Vigier P., Lederer E. Inhibition of virus-induced cell transformation by synthetic analogous of S-adenosyl homocysteine.- Biochem. Biophys.Res.Commun., 1975, v.65, N 4, p.1242−1249.
- Rosenberg B.H. The periodic structure of chromatin, implication for DNA function.- Biochem.Biophys.Res.Commun., 1976, v.72, p.1384−1391.
- Russev G., Tsanev R. Non random segregation of histones during chromatin replication.- Eur.J.Biochem., 1979, v.93, p.123−128.
- Russev G., Hancock R. Formation of hybrid nucleosomes containing new and old histones.- Nucl. Acids Res., 1981, v.9, p.4129−4137.
- Russev G., Hancock R. Assembly of new histones into nucleosomes and their distribution in replicating chromatin.-Proc.Natl.Acad.Sci USA, 1982, v.79, p.3145−3147.
- Salser W. Globin mRNA sequences: analysis of base pairingand evolutionary implications.- Cold Spring Harbor Symp. Quant.Biol., 1978, v.42, p.985−1002.
- Schlaeger E.J., Klempnauer K.-H. The structure of chromatinreplicated in vitro.- Eur.J. Biochem., 1978, v.89, p.567--574.
- Schlaeger E.-J., Knippers R. DNA-histone interaction in thevicinity of replication points.- Nucl.Acids.Res., 1979, v.6, p.645−656.
- Schlaeger E.-J. Replicative conformation of parental nucleosomes: salt sensitivity of deoxyribonucleic acid-histone interaction and alternation of histone H1 binding.- Biochemistry, 1982, v.21, p.3167−3174.
- Schmidt G., Thannhauser S.J. A method for the determinationof deoxyribonucleic acid, ribonucleic acid and phosphopro-teins in animal tissues.-J.Biol.Chem., 1945, v.161,p.83−89.- 159
- Seale R.L. Assembly of DNA and protein during replication in
- HeLa cells.- Nature, 1975, v.225., p.247−249.
- Seale R.L., Simpson R.T. Effects of cyclohexamide on chromatin biosynthesis.- J.Mol.Biol., 1975, v.94, p.479−501.
- Seale R.L. Temporal relationship of chromatin protein synthesis, DNA synthesis, and assembly of deoxyribonucleopro-tein.- Proc.Natl.Acad. Sci. USA, 1976, v.73, p.2270−2274.
- Seale R.L. Studies of the mode of segregation of histone Nubodies during replication in HeLa cells.- Cell, 1976, v.9, p.423−429.
- Seale R.L. Chromatin replication in vitro. Properties of a
- HeLa nuclear system.- Biochemistry, 1977, v.16, p.2847--2853.
- Seale R.L. Nucleosomes associated with newly replicated DNAhave an altered conformation.- Proc.Natl.Acad.Sci USA, 1978, v.75, p.2717−2721.
- Seidman M.M., Levine A.G., Weintraub H. The asymmetric segregation of parental nucleosomes during chromosome replication.- Cell, 1979, v.18, p.439−450.
- Sheinin R., Hombert J., Pearlman R.E. Eucaryotic DNA replication.- Ann. Rev. Biochem., 1978, v.47, p.277−316.
- Shelton R.E., Kang J., Wasserman P.M., De Paraphilia M.L.
- Shortle D., Nathans D. Regulatory mutants of simian virus40: constructed mutants with base substitutions at the origin of DNA replication.- J. Mol.Biol., 1979, v.131, p.801−817.
- Simpson R.T. Structure of the chromatosome, a chromatin particle containing 160 base pairs, of DNA and all the his-tones.- Biochemistry, 1978, v.17, p.5524−5531.
- Sneider T.W. Methylation of mammalian deoxyribonucleic acid.1. The destribution of 5-methylcytosine in pyrimidine-deoxyribonucleotide clusters in Novikoff hepatoma cell deoxyribonucleic acid.- J.Biol.Chem., 1971, v.246,p.4774−4783.
- Sneider T.W. Methylation of mammalian deoxyribonucleic acid.
- I. Terminal versus internal location of 5-methylcytosine in oligodeoxyribonucleotides from Novikoff Hepatoma cell deoxyribonucleic acid.- J.Biol.Chem., 1972, v.247, p.2872−2875.
- Sneider T.W. The 5*-cytosine in CCGG is methylated in twoeucaryotic DNA and Msp I is sensitive to methylation at this site.- Nucl. Acids Res., 1980, v.8, p.3829−3840.
- Solage A., Cedar H. Organization of 5-methylcytosine inchromosomal DNA.- Biochemistry, 1978, v.17, p.2934−2933.
- Solner-Webb B., Pelsenfeld G. A comparison of the digestionof nucleiv and chromatin by staphylococcal nuclease.- Biochemistry, 1975, v.14, p.2915−2920.-161
- Solomon R., Kays A.M., Herzberg H. Mouse nuclear DNA, 5-methylcytosiae contents, pyrlmidine isoplit destribution and electron microscopic appearance.- J.Mol.Biol. 1969″ v.43, p.581−589.
- Stalker D.M., Kolter R., Helinsky D.R. Nucleotide sequenceof the region of an origin of replication of the antibiotic resistance plasmide RGK".- Proc.Natl.Acad.Sci USA, 1979″ v.76, p.1150−1154.
- Sugino A., Hirose S., Okazaki R. BNA-linked nascent DNA fragments in Escherichia coli.- Proc.Natl.Acad.Sci USA, 1972, v.69, p.1863−1867.
- Terrioux C., Crepin M., Gros P., Robert—Gero M., Lederer E.
- Effett of S^deoxy-S-isobutyl-.adenosine (SiBA) on mouse mammary tumour cells and the expression of mouse mammary tumour virus.- Biochem.Biophys. Acta, 1978, v.83, N 2, p. 673−678.
- Thoma P., Koller Th., Klug A. Involvement of histone H1 in theorganization of the nucleosome and of the salt-dependent superstructures of chromatin.- J. Cell Biol., 1979, v.83, p.403−427.
- Tosi L., Granieri A., Scarano E. Enzymatic DNA modificationin isolated nuclei from developing sea urchin embryos.- Exp. Cell Res., 1972, v.72, p.257−264.
- Tosi L., Scarano E. Effect of trypsin on DNA methylation inisolated nuclei from developing sea urchin embryos.- Biochem.Biophys. Res. Commun., 1973, v.55, p.470−476.
- Tsanev R., Russev G. Distribution of newly synthesized histones during DNA replication.- Eur.J.Biochem., 1974, v.43, p.257−263.- 162
- Tseng B.Y., Goulian M. DNA synthesis in human lymphocytes.1.termediates in DNA synthesis in vitro and in vivo.-J.Mol.Biol., 1975, v.99, p.317−337.
- Tsubota Y., Waqar M.A., Devis L.R., Spotila Ь., Huberman J.
- A. Both parental deoxyribonucleic acid strands at each replication fork of replicating Simian Virus 40 chromosomes are cut by a sijagle-strand-specific endonuclease.-Biochemistry, 1982, v.21, p.2713−2718.
- Van der Ploeg L.H.T., Plavell R.A. DNA methylation in thehuman -globin locus in erythroid and nonerythroid tissues.- Cell, 1980, v.19, N 4, p.947−958.
- Vanyushin B.F., Tkacheva S.G., Belozersky A.N. Rare basesin animal DNA.- Nature, 1970, v.225, p.948−949.
- Varshavsky A.J., Bakayev V.V., Georgiev G.P. Heterogeneityof chromatin subunits in vitro and location of histone H1.-Nucl.Acids Res., 1976, v.3, p.477−492.
- Venkatesan N. Regulation of DNA chain elongation in SV 313cells in relation tp growth rate.- Biochem.Biophys.Acta, 1977, v.478, p.454−460.
- Weintraub Н. A possible role for histone in the synthesis of
- DNA.- Nature, 1972, v.240, p.449−453.
- Weintraub H., Palter K., Van Lente P. Histones H2A, H2B, H3and H4 a tetrameric complex in solutions of high salt.-Cell, 1975, v.6, p.85−110.
- Weintraub H. Cooperative alignment of Nu bodies during chromosome replication in the presence of cycloheximide.-Cell, 1976, v.9, p.419−422.
- Weissbach A. The functional roles of mammalian DNA polymerase archives of biochemistry and biophysics.-Arch.Biochem. Biophys., 1979, v.198, N 2, p.386−396.
- Wickremasighe R.G., Yaxley J.C., Hoffbrand A.V. Solubilization and partial characterization of multienzyme complex of DNA synthesis from human lumphoblasted cells.- Bur.J. Biochem., 1982, v.126, p.589−596.
- Zannis -Hadjopoulos M., Taylor M.W., Hand R. Inhibition of
- DNA chain elongation in a purine-auxotrophic mutant of Chinese hamster.- J. Cell Biol., 1980, v.85, p.777−785.
- Zimmerman J.В., Goldberg R.B. Molecular organization ofplant genome.- J. Cell Biol., 1975, v.67, p.471−477.
- Zimmerman S.B., Levin C.J. DNA ligase activity on chromatin and its analogous. Rejoining of DNA strands in poly-lysine DNA complexes and in reconstituted chromatins.-Biochemistry, 1975, v.14, p.1671−1677.