Исследование антител к фосфолипидам у детей с тромбозами, неврологическими и гематологическими заболеваниями
Диссертация
Наиболее часто в европейской и американской популяциях выявляются три точковые генетические мутации: мутация V фактора свертывания крови, мутация G20210A гена протромбина и С677Т в гене 5,10-метилентетрагидрофолатредуктазы, приводящий к развитию умеренной гипергомоцистинемии. Гетерозиготную мутацию (G1691A) в гене фактора V, получившую название лейденовской, обнаруживают у 20% больных США… Читать ещё >
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