Свойства мутантов пенициллинацилазы из Escherichia coli по положению 145 и 149 альфа субъединицы, 71, 384, 385 бета субъединицы в реакциях ацилирования аминосоединений и стереоселективного гидролиза амидов
Диссертация
Предшественник синтезируется как полипептид 92 кДа, состоящий из сигнального пептида, содержащего 26 аминокислот (а.к.), а также аи р-субъединиц (209 а.к. и 557 а.к., соответственно), разделенных эндопептидом (54 а.к.). Обе цепи, из которых состоит пенициллинацилаза, тесно переплетены и формируют пирамидальную структуру с глубокой чашеобразной выемкой в центре, на дне которой находится активный… Читать ещё >
Список литературы
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