Репрограммирование клеточных ответов макрофагов: новая стратегия управления воспалительным процессом
Диссертация
В фокусе воспаления макрофаги функционируют в неблагоприятных условиях. Для того чтобы противостоять токсическим эффектам цитокинов, свободных радикалов, бактериальных продуктов, таких как липополисахариды (ЛПС) и гипертермии, сопровождающей воспаление, макрофаги активируют самозащитный стресс-ответ (Knight, 2000; Ishii, et а!., 1999). Ключевым компонентом стресс-ответа являются белки теплового… Читать ещё >
Список литературы
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