Взаимодействие рицина с клетками гибридом, секретирующих антитела против его каталитической субъединицы
Диссертация
Согласно данным РСА, в молекуле ARTB функционирует только один углеводсвязывающий центр, расположенный в субдомене 1а. Его структура представлена на рис. 2. В ARTB, как и в RTB, Тгр37 образует гидрофобный контакт с молекулой галактозы. Аналогично Asp22 (Od1 и 0D2), Asn46 (ND2) и Gln35 (NE2) в RTB, в ARTB Asp22 (Od1-C4 gal), Asn46 (Nd2-C3 gal), Lys40 (Nz-C3 gal) и Gly25 (N-C4 gal) образуют… Читать ещё >
Список литературы
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